Low-dose radiation research insights in experimental animals: A gateway to therapeutic implications.

IF 1.7 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE Veterinary World Pub Date : 2024-10-01 Epub Date: 2024-10-07 DOI:10.14202/vetworld.2024.2253-2258
Nayanatara Arunkumar, Megha Gokul, Harini Narayanam, A K Ananya
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Abstract

In recent years, a significant research effort has been underway to explore the effects of low-dose radiation (LDR). Animal models play a key role in various fields of research, including biomedicine, pharmaceutical, environmental, and behavioral studies. The use of animal models has been an invaluable tool in radiation research for understanding radiation biology, assessing radiation risks, and developing strategies for radiation protection and medical management. In the present review, the initial part focuses on the deleterious effects of high-dose radiation, and in correlation to that, in the later part of the review, the emphasis has been given to experimental approaches to explore the beneficial effects of LDR using animal models. This review could help explore the innovative approach for future research targeting the therapeutic role of LDR in various diseases, including depression, Cancer, Parkinson's disease, and Alzheimer's disease.

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实验动物的低剂量辐射研究见解:通往治疗意义的门户。
近年来,人们对低剂量辐射(LDR)的影响进行了大量的研究。动物模型在包括生物医学、制药、环境和行为研究在内的各个研究领域发挥着关键作用。动物模型的使用已成为辐射研究中了解辐射生物学、评估辐射风险以及制定辐射防护和医疗管理战略的宝贵工具。在本综述中,第一部分重点介绍了高剂量辐射的有害影响,与此相关,在本文的后一部分,重点介绍了利用动物模型探索低剂量辐射有益影响的实验方法。本文综述有助于探索LDR在抑郁症、癌症、帕金森病和阿尔茨海默病等多种疾病中的治疗作用的创新方法。
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来源期刊
Veterinary World
Veterinary World Multiple-
CiteScore
3.60
自引率
12.50%
发文量
317
审稿时长
16 weeks
期刊介绍: Veterinary World publishes high quality papers focusing on Veterinary and Animal Science. The fields of study are bacteriology, parasitology, pathology, virology, immunology, mycology, public health, biotechnology, meat science, fish diseases, nutrition, gynecology, genetics, wildlife, laboratory animals, animal models of human infections, prion diseases and epidemiology. Studies on zoonotic and emerging infections are highly appreciated. Review articles are highly appreciated. All articles published by Veterinary World are made freely and permanently accessible online. All articles to Veterinary World are posted online immediately as they are ready for publication.
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