[Relationship Between Dementia and Lifestyle Diseases].

Abstract

As society ages, the number of people with dementia increases worldwide, and the prevention of dementia has become increasingly important. Lifestyle diseases are associated with the development of dementia, and preventing or controlling lifestyle diseases in middle-aged individuals is particularly important. Hypertension, diabetes, and dyslipidemia are associated with dementia. Hypertension is strongly associated with dementia, and strict blood pressure control is required. Among the drugs used to treat lifestyle diseases, some antihypertensive drugs(e.g., dihydropyridine calcium channel blockers, angiotensin 2 receptor blockers), hypoglycemic drugs(e.g., glucagon-like peptide 1 receptor agonists and sodium-glucose co-transporter-2 inhibitors), and statins may reduce the incidence of dementia. However, individual interventions for lifestyle diseases have only a limited effect in reducing the incidence of dementia. Comprehensive interventions may have significant effects. Clinicians involved in the management of lifestyle diseases need to have sound knowledge of these diseases and provide comprehensive management at an early stage.