A case report and literature review of rare isolated metastatic papillary thyroid carcinoma in the orbit.

IF 1.8 Q3 ENDOCRINOLOGY & METABOLISM Thyroid Research Pub Date : 2024-12-02 DOI:10.1186/s13044-024-00216-5
Behzad Khademi, Zahra Zia
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Abstract

Purpose: Orbital metastasis secondary to thyroid carcinoma is an exceedingly rare occurrence. In this case report, we present a rare isolated orbital metastasis of papillary thyroid carcinoma (PTC).

Methods: A case report and literature review study.

Result: A 55-year-old female, who presented with right-sided exophthalmos persisting for seven months and a week-long history of decreased visual acuity. Orbital computed tomography (CT) revealed a solid, isolated, well-circumscribed mass confined to the right intra-conal orbital cavity. Surgical excision via lateral orbitotomy confirmed the diagnosis of metastatic PTC.

Conclusion: Most cases reported in the literature have identified orbital masses concurrently with the initial diagnosis of thyroid carcinoma. In contrast, our patient exhibited ocular symptoms following a prolonged interval after normal post ablative iodine imaging, highlighting a significant delay in metastatic presentation. Moreover, the solid and well-defined nature of the metastatic orbital mass, confined solely to the orbital cavity without evidence of bony destruction, muscle involvement or intracranial extension in this patient, constitutes a distinctive clinical feature rarely documented in existing case reports.

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眼眶内罕见孤立性转移性甲状腺乳头状癌1例报告及文献复习。
目的:甲状腺癌继发眼眶转移极为罕见。在此病例报告中,我们报告一例罕见的孤立性甲状腺乳头状癌眼眶转移。方法:采用病例报告和文献复习法。结果:一名55岁女性,表现为右侧突出眼,持续7个月,视力下降史长达一周。眼眶计算机断层扫描(CT)显示一个实心的、孤立的、边界清楚的肿块,局限于右侧圆锥内眼眶腔。手术切除外侧眼窝证实转移性PTC的诊断。结论:文献报道的大多数病例在初次诊断甲状腺癌的同时发现了眼眶肿块。相比之下,我们的患者在消融后碘显像正常后出现眼部症状的时间间隔较长,突出了转移表现的显著延迟。此外,转移性眼眶肿块的坚固性和明确的性质,仅局限于眼眶腔,没有骨破坏、肌肉受累或颅内扩张的证据,构成了现有病例报告中很少记载的独特临床特征。
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来源期刊
Thyroid Research
Thyroid Research Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
3.10
自引率
4.50%
发文量
21
审稿时长
8 weeks
期刊最新文献
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