Implementation of a Patient-Specific Opioid Taper Calculator for Total Hip and Knee Arthroplasty: A Pre- and Post-Implementation Study

IF 3.8 2区 医学 Q1 ORTHOPEDICS Journal of Arthroplasty Pub Date : 2024-11-30 DOI:10.1016/j.arth.2024.11.040
Roberto A. Guzman MD , Jordan Ammons MBA , Jerald R. Westberg MPH , Andrew Schmidt MD
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Abstract

Background

Given the association between high opioid use and postoperative complications after total joint arthroplasty, it is important to prescribe opioids responsibly in the postoperative period. While many pain regimen protocols exist to try and limit opioid use, an optimal approach to narcotic prescription for arthroplasty patients is yet to be established. This study evaluated the effects of using an individualized opioid taper calculator for patients undergoing elective primary total hip arthroplasty (THA) and total knee arthroplasty (TKA). We hypothesized that using the calculator would lead to a decrease in the amount and variability of opioids prescribed postoperatively.

Methods

All primary THAs (117 precalculator and 105 postcalculator) and TKAs (172 precalculator and 139 postcalculator) meeting study inclusion and exclusion criteria were reviewed at a single academic hospital from January 2016 to December 2018 (precalculator) and January 2020 to December 2022 (postcalculator). The primary outcome measure was the quantity of opioids prescribed at discharge in morphine milligram equivalents between the two groups. Secondary measures included opioid refills, visual analog scale pain scores, and emergency department presentations or clinic calls due to pain. Statistical significance was defined as P <0.05.

Results

Implementation of the opioid taper calculator resulted in a 40% decrease in the median morphine milligram equivalent prescribed at discharge for both THA (450 versus 270; P < 0.0001) and TKA (450 versus 270; P < 0.0001) patients, respectively. There was no significant difference within the THA or TKA cohorts when comparing visual analog scale pain scores (THA, 3 versus 4; P = 0.47; TKA; 5 versus 6, P = 0.26), and no increase in percentage of patients who had emergency department visits (THA, 5.98 versus 0.95%; P = 0.069; TKA, 6.40 versus 11.5%; P = 0.155) or calls to the clinic for pain (THA, 17.1 versus 24.8%; P = 0.186; TKA, 36.6 versus 37.4%; P = 0.906) between the precalculator and postcalculator groups.

Conclusions

Our findings support the use of a patient-specific opioid taper calculator to decrease the volume and variability of narcotics prescribed postoperatively for THA and TKA pain management. Our findings confirmed the general applicability and effectiveness of the opioid taper calculator outside of its institution of origin.
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全髋关节和膝关节置换术患者特异性阿片类药物锥度计算器的实施:一项前后研究。
背景:考虑到全关节置换术后阿片类药物的高使用与术后并发症之间的关联,在术后期间负责任地开阿片类药物是很重要的。虽然存在许多疼痛方案来尝试和限制阿片类药物的使用,但关节置换术患者麻醉处方的最佳方法尚未建立。本研究评估了使用个体化阿片类药物锥度计算器对选择性原发性全髋关节置换术(THA)和全膝关节置换术(TKA)患者的影响。我们假设使用计算器会导致术后阿片类药物处方的数量和变异性的减少。方法:回顾2016年1月至2018年12月(计算器前)和2020年1月至2022年12月(计算器后)在一家学术医院进行的所有符合研究纳入和排除标准的原发性tha(117例,计算器后105例)和tka(172例,计算器后139例)。主要结局指标是两组出院时吗啡毫克当量(MME)处方阿片类药物的数量。次要测量包括阿片类药物补充,视觉模拟量表(VAS)疼痛评分,以及因疼痛引起的急诊科(ED)报告或诊所呼叫。P < 0.05为差异有统计学意义。结果:阿片类药物锥度计算器的实施导致THA出院时规定的中位MME减少40%(450比270;P < 0.0001)和TKA (450 vs 270;P < 0.0001)。在比较VAS疼痛评分时,THA组和TKA组之间没有显著差异(THA, 3分对4分;P = 0.47;TKA;5对6,P = 0.26), ED就诊的患者比例没有增加(THA, 5.98对0.95%;P = 0.069;TKA, 6.40 vs 11.5%;P = 0.155)或因疼痛就诊(THA, 17.1%对24.8%;P = 0.186;TKA 36.6%对37.4%;P = 0.906)。结论:我们的研究结果支持使用患者特异性阿片类药物用量计算器来减少全髋关节置换术和全髋关节置换术后疼痛管理中麻醉剂的用量和可变性。我们的研究结果证实了阿片类药物锥度计算器在其起源机构之外的普遍适用性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Arthroplasty
Journal of Arthroplasty 医学-整形外科
CiteScore
7.00
自引率
20.00%
发文量
734
审稿时长
48 days
期刊介绍: The Journal of Arthroplasty brings together the clinical and scientific foundations for joint replacement. This peer-reviewed journal publishes original research and manuscripts of the highest quality from all areas relating to joint replacement or the treatment of its complications, including those dealing with clinical series and experience, prosthetic design, biomechanics, biomaterials, metallurgy, biologic response to arthroplasty materials in vivo and in vitro.
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