Approximating the semantic space: word embedding techniques in psychiatric speech analysis.

IF 3 Q2 PSYCHIATRY Schizophrenia (Heidelberg, Germany) Pub Date : 2024-12-02 DOI:10.1038/s41537-024-00524-7
Claudio Palominos, Rui He, Karla Fröhlich, Rieke Roxanne Mülfarth, Svenja Seuffert, Iris E Sommer, Philipp Homan, Tilo Kircher, Frederike Stein, Wolfram Hinzen
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Abstract

Large language models provide high-dimensional representations (embeddings) of word meaning, which allow quantifying changes in the geometry of the semantic space in mental disorders. A pattern of a more condensed ('shrinking') semantic space marked by an increase in mean semantic similarity between words has been recently documented in psychosis across several languages. We aimed to explore this pattern further in picture descriptions provided by a transdiagnostic German sample of patients with schizophrenia spectrum disorders (SSD) (n = 42), major depression (MDD, n = 43), and healthy controls (n = 44). Compared to controls, both clinical groups showed more restricted dynamic navigational patterns as captured by the time series of semantic distances crossed, while also showing differential patterns in the total distances and trajectories navigated. These findings demonstrate alterations centred on the dynamics of the flow of meaning across the semantic space in SSD and MDD, preserving previous indications towards a shrinking semantic space in both cases.

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逼近语义空间:词嵌入技术在精神病学语音分析中的应用。
大型语言模型提供了词义的高维表示(嵌入),从而可以量化精神障碍中语义空间几何形状的变化。一种以单词之间的平均语义相似度增加为标志的更浓缩(“缩小”)的语义空间模式最近在几种语言的精神病中得到了记录。我们的目的是通过对德国精神分裂症谱系障碍(SSD) (n = 42)、重度抑郁症(MDD) (n = 43)和健康对照(n = 44)患者的跨诊断样本提供的图片描述进一步探索这一模式。与对照组相比,两个临床组都表现出更有限的动态导航模式,这是通过跨越语义距离的时间序列捕获的,同时在总距离和导航轨迹上也表现出不同的模式。这些发现表明,在SSD和MDD的语义空间中,以语义流动的动态为中心的变化,保留了两种情况下语义空间缩小的先前迹象。
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