The Importance of Stem Cells in the Treatment of Neuropathic Pain.

Farshad Hassanzadeh Kiabi, Tayebeh Khosravi, Saeed Gharooee Ahangar, Siavash Beiranvand
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Abstract

Many disorders, including heart, bone, cancer, liver, and brain disease, have been treated using stem cell therapy as a viable alternative. The somatosensory system is affected by a lesion, which leads to neuropathic pain (NP), and just a relatively tiny fraction of patients now receive effective care from existing pharmacological medications. There have been studies to show the effectiveness of various stem cells in reducing or treating experimental neurological pain, although these studies are uncommon in number. In this review, we will summarize the preclinical and clinical research that has been conducted on the effectiveness of several stem cell types, such as mesenchymal stem cells, bone-derived stem cells, and neural stem cells, in reducing neurological pain in this study.

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干细胞在神经性疼痛治疗中的重要性。
许多疾病,包括心脏、骨骼、癌症、肝脏和脑部疾病,已经将干细胞疗法作为一种可行的替代疗法来治疗。体感觉系统受到病变的影响,导致神经性疼痛(NP),现在只有一小部分患者从现有的药物治疗中得到有效的治疗。已经有研究表明各种干细胞在减少或治疗实验性神经疼痛方面的有效性,尽管这些研究在数量上并不常见。在这篇叙述性综述中,我们将总结几种干细胞类型(如间充质干细胞、骨源性干细胞和神经干细胞)在减轻神经性疼痛方面的有效性的临床前和临床研究。
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