Ultrasound Biomicroscopy for the Detection and Characterization of Anterior Segment Cysticercosis.

Clinical ophthalmology (Auckland, N.Z.) Pub Date : 2024-11-25 eCollection Date: 2024-01-01 DOI:10.2147/OPTH.S494556
Vaidehi D Bhatt, Kalpana D Bhatt, Deepak C Bhatt, Supriya Dabir, Tos T J M Berendschot, Roel J Erckens, Carroll A B Webers
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Abstract

Purpose: Ocular cysticercosis, caused by Taenia solium larvae, presents significant public health challenges, especially in regions with poor sanitation. Traditional imaging techniques often fail to detect anterior segment cysticercosis accurately, necessitating the exploration of more advanced diagnostic modalities like Ultrasound Biomicroscopy (UBM).

Patients and methods: A retrospective observational analysis was conducted on 18 eyes from 14 patients with cysticercosis involving the anterior segment. UBM imaging was performed using a Sonomed VuMax HD ultrasound biomicroscopy machine with a 50 MHz probe.

Results: In the study, 18 eyes from 18 patients were analyzed, revealing 12 cases of conjunctival cysticercosis, 4 of anterior chamber cysticercosis, and 2 of iris cysticercosis. Patients averaged 37.89 (± 16.2) years, with a male predominance. Conjunctival cysts appeared as clear masses, occasionally eliciting inflammatory reactions. Iris involvement caused thinning near the angle, while anterior chamber cysts could displace the lens, leading to iris bombe in some instances.

Conclusion: UBM emerges as a valuable diagnostic tool for anterior segment cysticercosis, providing detailed imaging superior to traditional methods. Its cost-effectiveness and accessibility make it particularly valuable, especially in resource-constrained settings. Future research should focus on validating UBM's diagnostic accuracy and exploring its role in monitoring disease progression and treatment response.

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超声生物显微镜对前段囊虫病的检测和表征。
目的:由猪带绦虫幼虫引起的眼囊虫病对公共卫生构成重大挑战,特别是在卫生条件差的地区。传统的成像技术往往不能准确地检测前段囊虫病,需要探索更先进的诊断方式,如超声生物显微镜(UBM)。患者与方法:对14例累及前段囊虫病患者18只眼进行回顾性观察分析。UBM成像使用Sonomed VuMax HD超声生物显微镜,带50 MHz探针。结果:对18例患者18只眼进行分析,结膜囊虫病12例,前房囊虫病4例,虹膜囊虫病2例。患者平均37.89(±16.2)岁,以男性为主。结膜囊肿表现为清晰的肿块,偶尔引起炎症反应。虹膜受累导致角附近变薄,而前房囊肿可移位晶状体,在某些情况下导致虹膜爆炸。结论:UBM是一种有价值的前段囊虫病诊断工具,提供了优于传统方法的详细成像。它的成本效益和可及性使其特别有价值,特别是在资源有限的情况下。未来的研究应侧重于验证UBM的诊断准确性,并探索其在监测疾病进展和治疗反应中的作用。
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