Onychomycosis caused by Aspergillus species belonging to section Circumdati.

Daiki Hayashi, Kayo Kashiwada-Nakamura, Hiromitsu Noguchi, Tadahiko Matsumoto, Takashi Yaguchi, Sayaka Ohara, Masahide Kubo, Katsunari Makino, Satoshi Fukushima
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Abstract

We encountered two cases of onychomycosis caused by Aspergillus (A.) subramanianii and A. sclerotiorum. These species belong to the Aspergillus section Circumdati, which is reportedly common in a wide range of habitats. The members of section Circumdati rarely cause onychomycosis. We report the second and fifth cases of A. subramanianii and A. sclerotiorum in the world. Positive findings in dermatophyte antigen kits helped us to diagnose these infections. These isolates were sensitive to ravuconazole, with a minimum inhibitory concentration of  0.5 μg/mL. They were successfully treated with oral fosravuconazole. We discuss 14 cases of onychomycosis caused by Aspergillus section Circumdati.

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由曲霉菌引起的甲癣病,属环孢菌科。
我们遇到了两例甲真菌病引起的曲霉(a) subramanianii和A. sclerotiorum。这些物种属于曲霉节环,据报道,这是常见的广泛的栖息地。圆形节的成员很少引起甲癣。本文报道了世界上第2例和第5例双胞单胞杆菌和菌核单胞杆菌。皮肤真菌抗原试剂盒的阳性结果有助于我们诊断这些感染。这些菌株对拉武康唑敏感,最低抑菌浓度为0.5 μg/mL。经口服fosravuconazole治疗成功。我们讨论了14例由圆形曲霉引起的甲真菌病。
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