A Novel Four-Step Regimen is Efficacious in Improving Uneven Skin Tone in Sensitive Skin Patients.

Abstract

Background: The appearance of dull skin, uneven skin tone, dark spots, and hyperpigmentation is often bothersome, especially in individuals with darker skin tones. Management of skin dyschromia can be difficult. Several topical ingredients, such as niacinamide and vitamin C, are clinically proven to inhibit pigmentation formation and improve overall skin tone. A skincare regimen formulated to minimize irregular melanin deposition levels has been specifically developed to help improve uneven skin tone for a more radiant appearance. This regimen consists of an exfoliating cleanser (EC), an antioxidant C serum (ACS), a day cream with SPF (DC), and a renewing cream (RC).

Methods: A 12-week in-use clinical regimen study was conducted to assess the efficacy, tolerability, and consumer perception of these products on 43 subjects with mild-to-moderate uneven skin tone. Assessments included clinical photography, tolerability, and a self-assessment questionnaire.

Results: There was a noticeable improvement in uneven skin tone, as shown in clinical photography across all timepoints (weeks 4, 8, and 12) compared to baseline. The regimen was safe and well tolerated for use and was highly acceptable among the subjects, with 81% of participants agreeing that their skin was more radiant since initiation of the regimen and 76% agreeing that the regimen had helped to significantly reduce the appearance of dark spots after 12 weeks of use. There were no reported adverse events.

Conclusion: Overall, these data show that this regimen is effective in reducing the appearance of uneven skin tone. J Drugs Dermatol. 2024;23(12):1072-1075. doi:10.36849/JDD.8220.