A Novel Four-Step Regimen is Efficacious in Improving Uneven Skin Tone in Sensitive Skin Patients.

IF 1.5 4区 医学 Q3 DERMATOLOGY Journal of Drugs in Dermatology Pub Date : 2024-12-01 DOI:10.36849/jdd.8220
Thu Q Nguyen, Christine Emesiani, Matthew Meckfessel
{"title":"A Novel Four-Step Regimen is Efficacious in Improving Uneven Skin Tone in Sensitive Skin Patients.","authors":"Thu Q Nguyen, Christine Emesiani, Matthew Meckfessel","doi":"10.36849/jdd.8220","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The appearance of dull skin, uneven skin tone, dark spots, and hyperpigmentation is often bothersome, especially in individuals with darker skin tones. Management of skin dyschromia can be difficult. Several topical ingredients, such as niacinamide and vitamin C, are clinically proven to inhibit pigmentation formation and improve overall skin tone. A skincare regimen formulated to minimize irregular melanin deposition levels has been specifically developed to help improve uneven skin tone for a more radiant appearance. This regimen consists of an exfoliating cleanser (EC), an antioxidant C serum (ACS), a day cream with SPF (DC), and a renewing cream (RC).</p><p><strong>Methods: </strong>A 12-week in-use clinical regimen study was conducted to assess the efficacy, tolerability, and consumer perception of these products on 43 subjects with mild-to-moderate uneven skin tone. Assessments included clinical photography, tolerability, and a self-assessment questionnaire.</p><p><strong>Results: </strong>There was a noticeable improvement in uneven skin tone, as shown in clinical photography across all timepoints (weeks 4, 8, and 12) compared to baseline. The regimen was safe and well tolerated for use and was highly acceptable among the subjects, with 81% of participants agreeing that their skin was more radiant since initiation of the regimen and 76% agreeing that the regimen had helped to significantly reduce the appearance of dark spots after 12 weeks of use. There were no reported adverse events.</p><p><strong>Conclusion: </strong>Overall, these data show that this regimen is effective in reducing the appearance of uneven skin tone. J Drugs Dermatol. 2024;23(12):1072-1075. doi:10.36849/JDD.8220.</p>","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"23 12","pages":"1072-1075"},"PeriodicalIF":1.5000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Drugs in Dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.36849/jdd.8220","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: The appearance of dull skin, uneven skin tone, dark spots, and hyperpigmentation is often bothersome, especially in individuals with darker skin tones. Management of skin dyschromia can be difficult. Several topical ingredients, such as niacinamide and vitamin C, are clinically proven to inhibit pigmentation formation and improve overall skin tone. A skincare regimen formulated to minimize irregular melanin deposition levels has been specifically developed to help improve uneven skin tone for a more radiant appearance. This regimen consists of an exfoliating cleanser (EC), an antioxidant C serum (ACS), a day cream with SPF (DC), and a renewing cream (RC).

Methods: A 12-week in-use clinical regimen study was conducted to assess the efficacy, tolerability, and consumer perception of these products on 43 subjects with mild-to-moderate uneven skin tone. Assessments included clinical photography, tolerability, and a self-assessment questionnaire.

Results: There was a noticeable improvement in uneven skin tone, as shown in clinical photography across all timepoints (weeks 4, 8, and 12) compared to baseline. The regimen was safe and well tolerated for use and was highly acceptable among the subjects, with 81% of participants agreeing that their skin was more radiant since initiation of the regimen and 76% agreeing that the regimen had helped to significantly reduce the appearance of dark spots after 12 weeks of use. There were no reported adverse events.

Conclusion: Overall, these data show that this regimen is effective in reducing the appearance of uneven skin tone. J Drugs Dermatol. 2024;23(12):1072-1075. doi:10.36849/JDD.8220.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
2.20
自引率
13.30%
发文量
289
审稿时长
3-6 weeks
期刊介绍: The Journal of Drugs in Dermatology (JDD) is a peer-reviewed publication indexed with MEDLINE®/PubMed® that was founded by the renowned Dr. Perry Robins MD. Founded in 2002, it offers one of the fastest routes to disseminate dermatologic information and is considered the fastest growing publication in dermatology. We present original articles, award-winning case reports, and timely features pertaining to new methods, techniques, drug therapy, and devices in dermatology that provide readers with peer reviewed content of the utmost quality. Our high standards of content are maintained through a balanced, peer-review process. Articles are reviewed by an International Editorial Board of over 160 renowned experts.
期刊最新文献
A Multi-Center, Double-Blind, Randomized, Comparator Controlled Trial Evaluating Topical Formulations for Skin Fragility of the Arms. A Novel Four-Step Regimen is Efficacious in Improving Uneven Skin Tone in Sensitive Skin Patients. An Update on the Off-Label Uses of Low-Dose Naltrexone in Dermatology. Cutaneous Collagenous Vasculopathy Treated With Pulsed Dye Laser: A Case Series and Literature Review. Effective With Minimal Side Effects: A Novel Treatment Regimen for Acne Vulgaris Using Multifunctional Ingredients.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1