Metrics for Perioperative Exercise in Patients Undergoing Lung Cancer Resection: A Systematic Review

Abstract

Perioperative exercise interventions have been shown to mitigate morbidity associated with lung resection. While these interventions have established a role in this patient population, there has been little discussion regarding which metrics are used to standardize perioperative exercise interventions. A better understanding of these metrics is needed to define best practices and ensure interventions are reproducible. A systematic review of the literature was performed using CINAHL, PubMed/MEDLINE, and SCOPUS. The initial review yielded a total of 3456 results. After review of titles and abstracts, 119 studies remained. The included studies underwent detailed review of the manuscript and 29 were found to meet the inclusion criteria for the review. A total of 29 studies were selected for inclusion. Included studies were completed on adult patients with diagnosis of lung cancer who underwent lung resection surgery and participated in a standardized exercise intervention before or after their surgery. The most common metrics used to grade exercise interventions were percent maximal workload (%Wmax) based on preoperative cardiopulmonary exercise testing (CPET), which was used in 41% of included studies, and symptom limited Borg rating of perceived exertion, which was used in 38% of included studies. There was significant variation in metrics used for tracking perioperative exercise interventions. Standardization of validated metrics for perioperative exercise interventions, specifically using percent of maximal workload and the Borg scale, would impact the ability to compare future studies and the effectiveness of exercise interventions.