Stem cell assisted low-intensity shockwave for erectile dysfunction treatment: Current perspective.

IF 3.4 3区环境科学与生态学 Q3 CELL & TISSUE ENGINEERING Regenerative Therapy Pub Date : 2024-11-20 eCollection Date: 2024-06-01 DOI:10.1016/j.reth.2024.11.006

Datesh Daneshwar, Yemin Lee, Abid Nordin

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Abstract

Stem cell therapy and low-intensity extracorporeal shockwave (LI-ECSW) are recognized as potential restorative therapies and have been used in the treatment of erectile dysfunction (ED). Stem cell therapy is well-known due to its attributed regenerative ability and thus can help to improve erectile function in patients with vasculogenic ED. Besides, current evidence also shows that LI-ECSW therapy can help stimulate cell recruitment and proliferation and promote angiogenesis and vascularization in the damaged tissue. Hence, due to the therapeutic and restorative effects of both therapies, the success of ED treatment can be elevated through a combination therapy between stem cell therapy and LI-ECSW. In this review, a detailed description and efficacy discussion of combination therapies between different types of stem cells and LI-ECSW therapy are described. Besides, other potential cell types to use together with LI-ECSW are also listed in this review. Thus, this review provides better insight on the efficacy of combination therapy for ED treatment.

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干细胞辅助低强度冲击波治疗勃起功能障碍：目前的观点。

干细胞疗法和低强度体外冲击波（LI-ECSW）被认为是潜在的恢复性疗法，并已被用于治疗勃起功能障碍（ED）。干细胞治疗因其再生能力而闻名，因此可以帮助改善血管源性ED患者的勃起功能。此外，目前的证据还表明，LI-ECSW治疗可以帮助刺激细胞募集和增殖，促进受损组织的血管生成和血管化。因此，由于两种疗法的治疗和恢复作用，可以通过干细胞治疗和LI-ECSW的联合治疗来提高ED治疗的成功率。在这篇综述中，详细描述了不同类型的干细胞和LI-ECSW联合治疗的疗效讨论。此外，本文还列出了其他可能与LI-ECSW一起使用的电池类型。因此，本综述对联合治疗ED的疗效提供了更好的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Regenerative Therapy Engineering-Biomedical Engineering

CiteScore

6.00

自引率

2.30%

发文量

106

审稿时长

49 days

期刊介绍： Regenerative Therapy is the official peer-reviewed online journal of the Japanese Society for Regenerative Medicine. Regenerative Therapy is a multidisciplinary journal that publishes original articles and reviews of basic research, clinical translation, industrial development, and regulatory issues focusing on stem cell biology, tissue engineering, and regenerative medicine.