Racial disparity among Native Americans in coronary artery bypass grafting: An analysis of national inpatient sample from 2015 to 2020.

Renxi Li, Deyanira J Prastein, Brian G Choi
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Abstract

Background: Disparities have been shown in the outcomes of coronary artery bypass grafting (CABG) in racial minorities. Although Native Americans are known to have a higher risk for cardiovascular diseases, the current literature on CABG outcomes for Native Americans remains notably limited, probably due to their limited population size. Thus, this study aimed to investigate racial disparities in CABG outcomes among Native Americans.

Methods: Patients who underwent CABG were identified in National Inpatient Sample database from last quarter of 2015 to 2020. A 1:2 propensity score matching was conducted between Native Americans and Caucasians to address preoperative differences in demographics, socioeconomic status, comorbidity, and hospital characteristics. In-hospital outcomes, length of stay (LOS), time from admission to operation, and total hospital charge were compared.

Results: There were 905 (0.54 %) Native Americans and 125,983 (74.91 %) Caucasians, where 1,838 Caucasians were matched to all the Native Americans. The in-hospital mortality rate was elevated in Native Americans but was not statistically different (2.87 % vs. 2.23 %, p = 0.43). However, Native Americans had a higher risk of cardiogenic shock (8.51 % vs. 6.2 %, p = 0.03). There was no difference in time from admission to operation (2.55 ± 0.11 vs. 2.73 ± 0.08 days, p = 0.20), LOS (9.82 ± 0.23 vs. 9.95 ± 0.20 days, p = 0.65), or the total hospital charge between the two groups (205,594 ± 5192.8 vs. 213,961 ± 4150.9 US dollars, p = 0.20).

Conclusion: Native Americans had a significantly higher risk of cardiogenic shock after CABG. However, in-house mortality and other parameters were not affected. These disparities highlight challenges that Native Americans encounter and emphasize the need for targeted interventions to ensure health equity.

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美洲原住民在冠状动脉搭桥术中的种族差异:2015 - 2020年全国住院患者样本分析
背景:少数种族的冠状动脉旁路移植术(CABG)的结果存在差异。虽然已知美洲原住民患心血管疾病的风险较高,但目前关于美洲原住民冠状动脉搭桥结果的文献仍然非常有限,这可能是由于他们的人口规模有限。因此,本研究旨在调查美洲原住民CABG结果的种族差异。方法:在2015年第四季度至2020年的全国住院患者样本数据库中识别行CABG的患者。在印第安人和白种人之间进行1:2倾向评分匹配,以解决术前人口统计学、社会经济地位、合并症和医院特征的差异。比较住院结果、住院时间(LOS)、入院至手术时间和总住院费用。结果:美洲原住民905人(0.54%),白种人125983人(74.91%),其中白种人与美洲原住民匹配1838人。印第安人的住院死亡率升高,但没有统计学差异(2.87% vs 2.23%, p=0.43)。然而,美洲原住民发生心源性休克的风险更高(8.51% vs 6.2%, p=0.03)。两组患者入院至手术时间(2.55±0.11 vs 2.73±0.08 d, p=0.20)、住院时间(9.82±0.23 vs 9.95±0.20 d, p=0.65)、住院总费用(205,594±5192.8 vs 213,961±4150.9美元,p=0.20)差异均无统计学意义。结论:美洲原住民在CABG后发生心源性休克的风险明显增高。但是,内部死亡率和其他参数没有受到影响。这些差异突出了美洲原住民面临的挑战,并强调需要采取有针对性的干预措施,以确保卫生公平。
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