Extemporaneous Compounding of Medicated Ointments.

Q4 Medicine International journal of pharmaceutical compounding Pub Date : 2024-11-01
Karen Nagel, Fatima Ali, Sarah Al-Khudari, Ayesha Khan, Khushbu Patel, Nikunj Patel, Archana Desai
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Abstract

Topical preparations represent a large percentage of compounded prescriptions, particularly in the area of dermatology. Properties of ointment bases vary greatly, and active ingredients are frequently added as aqueous or alcoholic solutions. Currently, there are no quantitative guidelines stating the various water and alcohol absorption capacity of different bases. A short experiment was designed to quantitate the amount of water or alcohol that could be absorbed by a series of ointment bases of varying types. Our findings may be used to assist compounding pharmacists in deciding what base is most suitable to use when considering the amount of water, alcohol, or any similar solvent needed to compound the preparation. A general overview of issues related to topical medication compounding is also provided in this article.

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临时配制药膏。
局部制剂占复方处方的很大比例,特别是在皮肤病学领域。药膏基质的性质变化很大,有效成分经常以水溶液或酒精溶液的形式加入。目前,还没有定量的指导方针来说明不同碱的各种水和酒精的吸收能力。设计了一个简短的实验来量化一系列不同类型的软膏基所能吸收的水或酒精的量。我们的发现可以用来帮助配药药剂师在考虑配药所需的水、酒精或任何类似溶剂的量时,决定最适合使用哪种碱。本文还提供了与局部药物复合有关的问题的一般概述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
62
期刊介绍: The International Journal of Pharmaceutical Compounding (IJPC) is a bi-monthly, scientific and professional journal emphasizing quality pharmaceutical compounding. IJPC is the only publication that covers pharmaceutical compounding topics relevant and necessary to empower pharmacists to meet the needs of today"s patients. No other publication features hands-on, how-to compounding techniques or the information that contemporary pharmacists need to provide individualized care.
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