Clinical Characteristics and Surgical Outcomes of the Full-thickness Macular Hole Without Focal Vitreomacular Traction: A Multicenter Retrospective Study.
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引用次数: 0
Abstract
Purpose: This study investigated the clinical features and surgical outcomes of full-thickness macular holes (FTMHs) without focal vitreomacular traction (VMT) and discusses possible underlying mechanisms.
Methods: This was a retrospective observational study included patients aged 18 years or older with stage 2 FTMHs who underwent pars plana vitrectomy at three hospitals between December 2016 and March 2024. Patients diagnosed without focal VMT in the macula were classified as VMT- and those with focal VMT were classified as VMT+. Medical records and comprehensive ophthalmologic examinations, including best-corrected visual acuity (BCVA) and optical coherence tomography assessments, were reviewed.
Results: This study analyzed 94 eyes that underwent surgery for stage 2 MHs. Patients in the VMT- were younger (VMT- vs VMT+: 63.6 vs 69.1 years, P = 0.008), had a longer axial length (AL) (25.2 vs 24.0 mm, P = 0.004), and had better preoperative BCVA [0.41 (20/43) vs 0.66 (20/74) logMAR, P = 0.002 ] compared with the VMT+. The VMT- had a higher prevalence of epiretinal proliferation (EP) compared with the VMT+ (76 vs 5 %, P<0.001). Postoperatively, no significant difference in visual outcomes was found between the two groups . VMT- showed significantly thicker central retinal thickness at 1 month (244 vs 201 μm, P = 0.021) and poorer external limiting membrane status at 1 month compared with the VMT+.
Conclusions: FTMHs without focal VMT were associated with younger age, longer AL, better baseline visual acuity, and a higher incidence of EP compared with FTMHs with VMT.
目的：探讨无局灶性玻璃体黄斑牵引（VMT）的全层黄斑孔（FTMHs）的临床特征和手术效果，并探讨可能的机制。方法：这是一项回顾性观察性研究，纳入了2016年12月至2024年3月在三家医院接受玻璃体切割手术的18岁及以上2期ftmh患者。诊断为黄斑无局灶性VMT的患者分为VMT-型，有局灶性VMT的患者分为VMT+型。回顾了医疗记录和综合眼科检查，包括最佳矫正视力（BCVA）和光学相干断层扫描评估。结果：本研究分析了94只接受2期MHs手术的眼睛。VMT-组患者更年轻（VMT- vs VMT+: 63.6 vs 69.1岁，P = 0.008），轴向长度（AL）更长（25.2 vs 24.0 mm, P = 0.004），术前BCVA更好[0.41 (20/43)vs 0.66 (20/74) logMAR, P = 0.002]。VMT-与VMT+相比，VMT-有更高的视网膜前增生（EP）患病率（76% vs 5%）。结论：无局灶性VMT的ftmh与合并VMT的ftmh相比，年龄更年轻，AL更长，基线视力更好，EP发生率更高。
期刊介绍：
RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice.
In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color.
Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.
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