Impact of bariatric surgery on infertility in obese women: a systematic review and meta-analysis.

IF 1.7 Q2 MEDICINE, GENERAL & INTERNAL Annals of Medicine and Surgery Pub Date : 2024-10-23 eCollection Date: 2024-12-01 DOI:10.1097/MS9.0000000000002657
Behnam R Makhsosi, Pourya Ghobadi, Masoumeh Otaghi, Zeinab Tardeh
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Abstract

Background: The prevalence of obesity is increasing worldwide, with several consequences, including reduced fertility in both men and women. One of the ways to reduce weight is bariatric surgery. The aim of this systematic review and meta-analysis study was to evaluate the effectiveness of bariatric surgery on weight loss and subsequent improvement of fertility in obese infertile women.

Methods: Several databases were searched using MESH terms to investigate the studies that evaluated the fertility rates after bariatric surgery in infertile obese women. Related data were obtained and analyzed using Stata software with a P-value ≤0.05, which was considered as significant.

Results: Of the 283 articles related to the purpose of this study, 9 articles, including 231 obese infertile women, were included in the study. BMI before surgery was 42.2 [95% CI= 39.2-45.2] and BMI after surgery was 31.9 (95% CI= 28.9-34.8), which shows the significance of weight loss after bariatric surgery. Conception rate after bariatric surgery weight loss was increased and was 67% (95% CI= 47-87%, P-value <0.05).

Conclusions: Bariatric surgery had a significant effect on the reduction of BMI and subsequent significant improvement of fertility in obese infertile women.

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减肥手术对肥胖女性不孕症的影响:系统回顾和荟萃分析。
背景:世界范围内肥胖的患病率正在上升,这带来了一些后果,包括男性和女性的生育能力下降。减肥的方法之一是减肥手术。本系统综述和荟萃分析研究的目的是评估减肥手术对肥胖不育妇女体重减轻和随后生育能力改善的有效性。方法:使用MESH检索多个数据库,调查评估不孕肥胖妇女减肥手术后生育率的研究。使用Stata软件获取相关数据并进行分析,p值≤0.05为差异有统计学意义。结果:283篇与本研究目的相关的文献中,有9篇纳入研究,包括231名肥胖不孕妇女。术前BMI为42.2 [95% CI= 39.2-45.2],术后BMI为31.9 (95% CI= 28.9-34.8),显示减肥手术后体重减轻的显著性。减肥手术减肥后受孕率增加,为67% (95% CI= 47-87%, p值)结论:减肥手术对肥胖不育妇女BMI的降低和随后生育能力的显著改善有显著作用。
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来源期刊
Annals of Medicine and Surgery
Annals of Medicine and Surgery MEDICINE, GENERAL & INTERNAL-
自引率
5.90%
发文量
1665
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