Brugada Phenocopy Induced by BRAF and MEK Inhibitors in a Lung Adenocarcinoma

IF 2.3 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular Electrophysiology Pub Date : 2024-12-10 DOI:10.1111/jce.16533
Leonardo Portolan, Alessandro Ruzzarin, Francesca Vassanelli, Flavio Ribichini, Giacomo Mugnai
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Abstract

Management of patients with drug-induced type 1 Brugada pattern is complex and controversial. We report the case of a 66-year-old man affected by metastatic lung adenocarcinoma with type 1 Brugada phenocopy at electrocardiogram (ECG) after initiation of an oncological therapy with BRAF and MEK inhibitors.

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BRAF和MEK抑制剂在肺腺癌中诱导Brugada表型
药物致1型Brugada型患者的治疗是一个复杂而有争议的问题。我们报告了一例66岁男性转移性肺腺癌患者,在接受BRAF和MEK抑制剂的肿瘤治疗后,心电图显示1型Brugada表型。
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来源期刊
CiteScore
5.20
自引率
14.80%
发文量
433
审稿时长
3-6 weeks
期刊介绍: Journal of Cardiovascular Electrophysiology (JCE) keeps its readership well informed of the latest developments in the study and management of arrhythmic disorders. Edited by Bradley P. Knight, M.D., and a distinguished international editorial board, JCE is the leading journal devoted to the study of the electrophysiology of the heart.
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