Sameera Ramjan, Peter D. Cole, Melanie Blair-Thies, Lewis B. Silverman, Amy Fredrickson, Adrian Schembri, Jennifer J. Greene Welch, Justine Kahn, Kara M. Kelly, Thai-Hoa Tran, Bruno Michon, Lisa Gennarini, Stephen A. Sands
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引用次数: 0
Abstract
Treatment of acute lymphoblastic leukemia (ALL) is associated with neurocognitive deficits in young children. While computerized measures have been utilized in pediatric oncology research, they exclude patients below the age of 4 years. Patients enrolled on “Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents” were offered participation in an optional neurocognitive study. Three-year old patients did not differ from 4-year-old patients in their ability to perform or complete the tests. Including patients diagnosed at age 3 will serve to improve our understanding of at-risk patients and their neurocognitive trajectory both during and after treatment.
期刊介绍：
Pediatric Blood & Cancer publishes the highest quality manuscripts describing basic and clinical investigations of blood disorders and malignant diseases of childhood including diagnosis, treatment, epidemiology, etiology, biology, and molecular and clinical genetics of these diseases as they affect children, adolescents, and young adults. Pediatric Blood & Cancer will also include studies on such treatment options as hematopoietic stem cell transplantation, immunology, and gene therapy.
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