{"title":"Endovascular thrombectomy for acute ischemic stroke complicated with systemic light chain amyloidosis: Two case reports","authors":"Yongjie Bai, Bingjie Sun, Jiahui Su","doi":"10.1016/j.jstrokecerebrovasdis.2024.108181","DOIUrl":null,"url":null,"abstract":"<div><div>Systemic light chain amyloidosis (AL) is a non-proliferative plasma cell disease characterized by the deposition of fragments of immunoglobulin light or heavy chain in tissues. There has been no relevant report on the treatment of vascularization during the acute stage of acute ischemic stroke (AIS) complicated with AL. This paper presented two cases of AIS complicated with AL that were treated with intravenous thrombolysis (IVT) and mechanical thrombectomy (MT). The combination of aspiration thrombectomy and IVT might be feasible for patients with AIS complicated with AL.</div></div>","PeriodicalId":54368,"journal":{"name":"Journal of Stroke & Cerebrovascular Diseases","volume":"34 2","pages":"Article 108181"},"PeriodicalIF":2.0000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Stroke & Cerebrovascular Diseases","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1052305724006244","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Systemic light chain amyloidosis (AL) is a non-proliferative plasma cell disease characterized by the deposition of fragments of immunoglobulin light or heavy chain in tissues. There has been no relevant report on the treatment of vascularization during the acute stage of acute ischemic stroke (AIS) complicated with AL. This paper presented two cases of AIS complicated with AL that were treated with intravenous thrombolysis (IVT) and mechanical thrombectomy (MT). The combination of aspiration thrombectomy and IVT might be feasible for patients with AIS complicated with AL.
期刊介绍：
The Journal of Stroke & Cerebrovascular Diseases publishes original papers on basic and clinical science related to the fields of stroke and cerebrovascular diseases. The Journal also features review articles, controversies, methods and technical notes, selected case reports and other original articles of special nature. Its editorial mission is to focus on prevention and repair of cerebrovascular disease. Clinical papers emphasize medical and surgical aspects of stroke, clinical trials and design, epidemiology, stroke care delivery systems and outcomes, imaging sciences and rehabilitation of stroke. The Journal will be of special interest to specialists involved in caring for patients with cerebrovascular disease, including neurologists, neurosurgeons and cardiologists.
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