Predictors of Retention in the 1Florida Alzheimer's Disease Research Center (ADRC) Over Two Waves.

IF 2.2 3区医学 Q2 GERONTOLOGY Journal of Applied Gerontology Pub Date : 2024-12-10 DOI:10.1177/07334648241302159

Shanna L Burke, Warren Barker, Adrienne Grudzien, Maria T Greig-Custo, Raquel Behar, Rosemarie A Rodriguez, Monica Rosselli, Idaly Velez Uribe, David A Loewenstein, Miriam J Rodriguez, Cesar Chirinos, Carlos Quinonez, Joanna Gonzalez, Yaimara Gonzalez Pineiro, Mileidys Herrera, Malek Adjouadi, Michael Marsiske, Ranjan Duara

{"title":"Predictors of Retention in the 1Florida Alzheimer's Disease Research Center (ADRC) Over Two Waves.","authors":"Shanna L Burke, Warren Barker, Adrienne Grudzien, Maria T Greig-Custo, Raquel Behar, Rosemarie A Rodriguez, Monica Rosselli, Idaly Velez Uribe, David A Loewenstein, Miriam J Rodriguez, Cesar Chirinos, Carlos Quinonez, Joanna Gonzalez, Yaimara Gonzalez Pineiro, Mileidys Herrera, Malek Adjouadi, Michael Marsiske, Ranjan Duara","doi":"10.1177/07334648241302159","DOIUrl":null,"url":null,"abstract":"Background: Attrition is a significant methodological concern in longitudinal studies. Sample loss can limit generalizability and compromise internal validity. Methods: Wave one (n = 346) and wave two follow-ups (n = 196) of the 1Florida ADRC clinical core were examined using a 24-month visit window. Results: The sample (59% Hispanic) demonstrated retention rates of 77.2% and 86.2% in waves one and two, respectively. Predictors of lower retention in wave one included older age, amnestic MCI or dementia, and lower cognition and function scores. Completing a baseline MRI and lack of hippocampal atrophy were associated with higher retention in both waves. In wave two, a greater neighborhood disadvantage score was associated with attrition. Discussion: Predictors of retention changed over time, possibly due to the early withdrawal of the most vulnerable in the initial wave. Understanding predictors of retention can facilitate retention strategies, reduce attrition, and increase the validity of findings.","PeriodicalId":47970,"journal":{"name":"Journal of Applied Gerontology","volume":" ","pages":"7334648241302159"},"PeriodicalIF":2.2000,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Gerontology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/07334648241302159","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GERONTOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Attrition is a significant methodological concern in longitudinal studies. Sample loss can limit generalizability and compromise internal validity. Methods: Wave one (n = 346) and wave two follow-ups (n = 196) of the 1Florida ADRC clinical core were examined using a 24-month visit window. Results: The sample (59% Hispanic) demonstrated retention rates of 77.2% and 86.2% in waves one and two, respectively. Predictors of lower retention in wave one included older age, amnestic MCI or dementia, and lower cognition and function scores. Completing a baseline MRI and lack of hippocampal atrophy were associated with higher retention in both waves. In wave two, a greater neighborhood disadvantage score was associated with attrition. Discussion: Predictors of retention changed over time, possibly due to the early withdrawal of the most vulnerable in the initial wave. Understanding predictors of retention can facilitate retention strategies, reduce attrition, and increase the validity of findings.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

佛罗里达阿尔茨海默病研究中心（ADRC）两波脑潴留预测因子

背景：损耗是纵向研究中一个重要的方法论问题。样本丢失会限制概括性并损害内部有效性。方法：采用24个月的随访窗口，对佛罗里达州1例ADRC临床核心患者的第一波（n = 346）和第二波（n = 196）进行随访。结果：该样本（59%为西班牙裔）在第一波和第二波的保留率分别为77.2%和86.2%。第一波记忆力较低的预测因素包括年龄较大、失忆性轻度认知障碍或痴呆，以及认知和功能评分较低。完成基线MRI检查和没有海马萎缩与两波中较高的脑潴留有关。在第二波中，更大的邻里劣势得分与人员流失有关。讨论：留存率的预测因子会随着时间的推移而改变，这可能是由于在最初的浪潮中最脆弱的玩家会提前退出。了解留存率的预测因素可以促进留存策略，减少人员流失，提高调查结果的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Journal of Applied Gerontology GERONTOLOGY-

CiteScore

5.10

自引率

13.30%

发文量

202

期刊介绍： The Journal of Applied Gerontology (JAG) is the official journal of the Southern Gerontological Society. It features articles that focus on research applications intended to improve the quality of life of older persons or to enhance our understanding of age-related issues that will eventually lead to such outcomes. We construe application broadly and encourage contributions across a range of applications toward those foci, including interventions, methodology, policy, and theory. Manuscripts from all disciplines represented in gerontology are welcome. Because the circulation and intended audience of JAG is global, contributions from international authors are encouraged.