Clinical and epidemiological aspects of spondylodiscitis in a tertiary care hospital in South India.

Le infezioni in medicina Pub Date : 2024-12-01 eCollection Date: 2024-01-01 DOI:10.53854/liim-3204-7
Latha Thimmappa, Saraswathi Hebbar, Shyamasunder N Bhat
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Abstract

This study aims to bridge the informational gap regarding the clinical and epidemiological aspects of spondylodiscitis in India, addressing the dearth of substantial evidence in this domain. This study was conducted in a tertiary care hospital over three years, involving 145 adult patients diagnosed with spondylodiscitis. Among them, 28 (19.3%) had Brucellar spondylodiscitis with a younger mean age of 40.1 years, 76 (52.4%) had tubercular spondylodiscitis with a higher mean age of 50.7 years, and 27 (18.6%) had pyogenic spondylodiscitis. Common symptoms included pain while walking (82.1% Brucellar, 93.4% TB, 77.8% pyogenic), fever (39.3% Brucellar, 38.2% TB, 33.3% pyogenic), and limb weakness (25% Brucellar, 46.1% TB, 66.7% pyogenic). CRP (mg/L) levels were elevated in Brucellar (mean 58.75) and pyogenic (mean 60.4) spondylodiscitis patients, with debridement and decompression performed in 50% Brucellar, 55.3% tubercular, and 70.4% pyogenic patients. The study reveals the clinical and epidemiological aspects of spondylodiscitis in South India, contributing to the enrichment of existing knowledge in diagnosis and management.

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南印度一家三级医院脊柱炎的临床和流行病学方面。
本研究旨在弥合关于印度脊柱炎临床和流行病学方面的信息差距,解决这一领域缺乏实质性证据的问题。本研究是在一家三级医院进行的,为期三年,涉及145名诊断为脊椎椎间盘炎的成年患者。其中,布鲁氏菌性椎间盘炎28例(19.3%),平均年龄较小,为40.1岁;结核性椎间盘炎76例(52.4%),平均年龄较大,为50.7岁;化脓性椎间盘炎27例(18.6%)。常见症状包括行走疼痛(82.1%布鲁氏菌,93.4%结核,77.8%化脓性)、发热(39.3%布鲁氏菌,38.2%结核,33.3%化脓性)和肢体无力(25%布鲁氏菌,46.1%结核,66.7%化脓性)。c反应蛋白(mg/L)水平在布鲁氏菌(平均58.75)和化脓性(平均60.4)脊柱椎间盘炎患者中升高,50%的布鲁氏菌、55.3%的结核和70.4%的化脓性患者进行了清创减压。该研究揭示了南印度脊柱炎的临床和流行病学方面,有助于丰富现有的诊断和管理知识。
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Clinical and epidemiological aspects of spondylodiscitis in a tertiary care hospital in South India. Evaluation of a training program on hand hygiene for healthcare workers in a second-level hospital in southern Italy during the COVID-19 pandemic. Crimean-Congo haemorrhagic fever (CCHF): present and future therapeutic armamentarium. Infectious disease outbreaks in the wake of natural flood disasters: global patterns and local implications. Leprosy with subsequent type 2 reaction masquerading as cutaneous tuberculosis: a case report and diagnostic pitfalls in a non-endemic area.
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