Seronegative rheumatoid arthritis found in an 85-year-old woman during preoperative investigations for knee replacement surgery for osteoarthritis.

IF 0.9 Q4 RHEUMATOLOGY Modern rheumatology case reports Pub Date : 2025-07-25 DOI:10.1093/mrcr/rxae076
Haruka Nakano, Makoto Hirao, Dong Seop Kim, Gensuke Okamura, Yoshihiko Hoshida, Takaaki Noguchi, Yuki Etani, Kosuke Ebina, Seiji Okada, Jun Hashimoto, Shiro Ohshima
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Abstract

This report describes the case of an 85-year-old woman who was found to have seronegative rheumatoid arthritis during preoperative investigations for knee replacement surgery for osteoarthritis. Follow-up for knee osteoarthritis was continued for many years without any symptoms involving other joints. Before total knee arthroplasty for osteoarthritis, preoperative investigations revealed a highly inflammatory state. After differential diagnosis, seronegative rheumatoid arthritis was diagnosed. Even in preoperative investigations before total knee arthroplasty for very old patients with osteoarthritis, the possibility of rheumatoid arthritis developing should always be kept in mind.

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血清阴性类风湿关节炎发现于85岁妇女在术前调查膝关节置换手术骨关节炎。
本报告描述了一例85岁的妇女,在为骨关节炎进行膝关节置换手术的术前检查中发现血清阴性类风湿关节炎。对膝关节骨性关节炎的随访持续多年,无其他关节出现任何症状。在全膝关节置换术治疗骨关节炎之前,术前调查显示高度炎症状态。鉴别诊断为血清阴性类风湿关节炎。即使在高龄骨关节炎患者全膝关节置换术前的术前检查中,类风湿关节炎发展的可能性也应始终牢记在心。
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