Patrick Papa, Brandon Whitefield, Deborah S. Mortensen, Dan Cashion, Dehua Huang, Eduardo Torres, Jason Parnes, John Sapienza, Joshua Hansen, Matthew Correa, Mercedes Delgado, Roy Harris, Sayee Hegde, Stephen Norris, Sogole Bahmanyar, Veronique Plantevin-Krenitsky, Zheng Liu, Katerina Leftheris, Ashutosh Kulkarni, Brydon Bennett, Eun Mi Hur, Garth Ringheim, Godrej Khambatta, Henry Chan, Jeffrey Muir, Kate Blease, Kelven Burnett, Laurie LeBrun, Lisa Morrison, Maria Celeridad, Roli Khattri, Brian E. Cathers
{"title":"Correction to “Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005”","authors":"Patrick Papa, Brandon Whitefield, Deborah S. Mortensen, Dan Cashion, Dehua Huang, Eduardo Torres, Jason Parnes, John Sapienza, Joshua Hansen, Matthew Correa, Mercedes Delgado, Roy Harris, Sayee Hegde, Stephen Norris, Sogole Bahmanyar, Veronique Plantevin-Krenitsky, Zheng Liu, Katerina Leftheris, Ashutosh Kulkarni, Brydon Bennett, Eun Mi Hur, Garth Ringheim, Godrej Khambatta, Henry Chan, Jeffrey Muir, Kate Blease, Kelven Burnett, Laurie LeBrun, Lisa Morrison, Maria Celeridad, Roli Khattri, Brian E. Cathers","doi":"10.1021/acs.jmedchem.4c02898","DOIUrl":null,"url":null,"abstract":"In Figure 3 and the related text, Asp508 was incorrectly labeled as Asp409 due to typographical error in figure preparation. The corrected figure and updated line of text are as follow:<named-content content-type=\"anchor\" r type=\"simple\"></named-content> Figure 3. Docking model of <b>3</b> bound in the ATP pocket of PKC-θ (PDB ID 1XJD used for docking studies). Page 11889: “The basic piperidine amine forms two salt-bridges with side-chain carboxylates of Asp465 and catalytic residue Asp522 and forms a third hydrogen bond to the backbone carbonyl of Asp508.” This article has not yet been cited by other publications.","PeriodicalId":46,"journal":{"name":"Journal of Medicinal Chemistry","volume":"10 1","pages":""},"PeriodicalIF":6.8000,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medicinal Chemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1021/acs.jmedchem.4c02898","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
In Figure 3 and the related text, Asp508 was incorrectly labeled as Asp409 due to typographical error in figure preparation. The corrected figure and updated line of text are as follow: Figure 3. Docking model of 3 bound in the ATP pocket of PKC-θ (PDB ID 1XJD used for docking studies). Page 11889: “The basic piperidine amine forms two salt-bridges with side-chain carboxylates of Asp465 and catalytic residue Asp522 and forms a third hydrogen bond to the backbone carbonyl of Asp508.” This article has not yet been cited by other publications.
期刊介绍：
The Journal of Medicinal Chemistry is a prestigious biweekly peer-reviewed publication that focuses on the multifaceted field of medicinal chemistry. Since its inception in 1959 as the Journal of Medicinal and Pharmaceutical Chemistry, it has evolved to become a cornerstone in the dissemination of research findings related to the design, synthesis, and development of therapeutic agents.
The Journal of Medicinal Chemistry is recognized for its significant impact in the scientific community, as evidenced by its 2022 impact factor of 7.3. This metric reflects the journal's influence and the importance of its content in shaping the future of drug discovery and development. The journal serves as a vital resource for chemists, pharmacologists, and other researchers interested in the molecular mechanisms of drug action and the optimization of therapeutic compounds.
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