EUS-directed transduodenal ERCP in concomitant gastric outlet and biliary obstruction

IF 7.5 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Gastrointestinal endoscopy Pub Date : 2025-04-01 DOI:10.1016/j.gie.2024.12.003
Vivek Kesar MD , William F. Abel MD , Jay Bapaye MD , Reid D. Wasserman DO , Jonathan Rozenberg DO , Subhash Garikipati MD , Klaus E. Mönkemüller MD , Varun Kesar MD , Paul Yeaton MD
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Abstract

Background and Aims

Patients with concomitant gastric outlet obstruction (GOO) and biliary obstruction often have limited management options, particularly in the setting of severe debility. We detail the use of EUS-guided gastroduodenal placement of a lumen-apposing metal stent (LAMS) as a conduit for transduodenal ERCP: EUS-directed transduodenal ERCP.

Methods

Nine patients who developed GOO with indwelling biliary metal stents or with anticipated biliary stent placement were retrospectively included.

Results

A 20 mm × 10 mm LAMS was deployed for creation of gastroduodenostomy in all patients. ERCP was performed via the gastroduodenal LAMS with resolution of jaundice in 100% of patients. GOO score improved to 3 in all patients.

Conclusions

This study demonstrates excellent outcomes (resolution of jaundice and GOO) in all chronically ill, poor surgical candidates. Placement of a LAMS allowed for both treatment of GOO and ERCP access for present and future stent exchange.

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eus引导的经十二指肠ERCP在并发胃出口和胆道梗阻中的应用。
背景和目的:伴有胃出口梗阻(GOO)和胆道梗阻的患者通常只有有限的治疗选择,特别是在严重虚弱的情况下。我们详细介绍了EUS引导下胃十二指肠放置腔旁金属支架(LAMS)作为经十二指肠ERCP的导管:EUS引导的经十二指肠ERCP (EDDE)。方法:回顾性分析9例留置胆道金属支架或预期放置胆道金属支架后发生粘稠的患者。结果:所有患者均采用20mm × 10mm的LAMS进行胃十二指肠吻合。ERCP通过胃十二指肠LAMS进行,100%的患者黄疸消退。所有患者的GOOSS评分均提高至3分。结论:本研究显示了所有慢性疾病,不良手术候选人的良好结果(黄疸和粘粘症的消退)。LAMS既可以治疗粘稠症,也可以为当前和未来的支架置换提供ERCP通道。
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来源期刊
Gastrointestinal endoscopy
Gastrointestinal endoscopy 医学-胃肠肝病学
CiteScore
10.30
自引率
7.80%
发文量
1441
审稿时长
38 days
期刊介绍: Gastrointestinal Endoscopy is a journal publishing original, peer-reviewed articles on endoscopic procedures for studying, diagnosing, and treating digestive diseases. It covers outcomes research, prospective studies, and controlled trials of new endoscopic instruments and treatment methods. The online features include full-text articles, video and audio clips, and MEDLINE links. The journal serves as an international forum for the latest developments in the specialty, offering challenging reports from authorities worldwide. It also publishes abstracts of significant articles from other clinical publications, accompanied by expert commentaries.
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