Bayesian hierarchical network autocorrelation models for estimating direct and indirect effects of peer hospitals on outcomes of hospitalized patients.

IF 1.3 Q3 COMPUTER SCIENCE, THEORY & METHODS Applied Network Science Pub Date : 2024-01-01 Epub Date: 2024-06-14 DOI:10.1007/s41109-024-00627-1
Guanqing Chen, A James O'Malley
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Abstract

When an hypothesized peer effect (also termed social influence or contagion) is believed to act between units (e.g., hospitals) above the level at which data is observed (e.g., patients), a network autocorrelation model may be embedded within a hierarchical data structure thereby formulating the peer effect as a dependency between latent variables. In such a situation, a patient's own hospital can be thought of as a mediator between the effects of peer hospitals and their outcome. However, as in mediation analyses, there may be interest in allowing the effects of peer units to directly impact patients of other units. To accommodate these possibilities, we develop two hierarchical network autocorrelation models that allow for direct and indirect peer effects between hospitals when modeling individual outcomes of the patients cared for at the hospitals. A Bayesian approach is used for model estimation while a simulation study assesses the performance of the models and sensitivity of results to different prior distributions. We construct a United States New England region patient-sharing hospital network and apply newly developed Bayesian hierarchical models to study the diffusion of robotic surgery and hospital peer effects in patient outcomes using a cohort of United States Medicare beneficiaries in 2016 and 2017. The comparative fit of models to the data is assessed using Deviance information criteria tailored to hierarchical models that include peer effects as latent variables.

Supplementary information: The online version contains supplementary material available at 10.1007/s41109-024-00627-1.

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贝叶斯分层网络自相关模型用于估算同级医院对住院患者预后的直接和间接影响。
当假设的同伴效应(也称为社会影响或传染)被认为在观察到数据的水平(例如,患者)之上的单位(例如,医院)之间起作用时,可以在分层数据结构中嵌入网络自相关模型,从而将同伴效应表示为潜在变量之间的依赖关系。在这种情况下,患者自己的医院可以被认为是同行医院的影响和他们的结果之间的中介。然而,正如在中介分析中一样,可能有兴趣允许同行单位的影响直接影响其他单位的患者。为了适应这些可能性,我们开发了两个层次网络自相关模型,在对医院照顾的患者的个体结果建模时,允许医院之间的直接和间接对等效应。模型估计采用贝叶斯方法,仿真研究评估了模型的性能和结果对不同先验分布的敏感性。我们构建了一个美国新英格兰地区患者共享医院网络,并应用新开发的贝叶斯分层模型,研究机器人手术的扩散和医院同伴效应对2016年和2017年美国医疗保险受益人的患者结局的影响。模型与数据的比较拟合是使用Deviance信息标准来评估的,该标准是为分层模型量身定制的,其中包括同伴效应作为潜在变量。补充信息:在线版本包含补充资料,提供地址为10.1007/s41109-024-00627-1。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Applied Network Science
Applied Network Science Multidisciplinary-Multidisciplinary
CiteScore
4.60
自引率
4.50%
发文量
74
审稿时长
5 weeks
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