Healthy aging in individuals born after assisted reproductive technology is a research area for the future

IF 17 Q1 CELL BIOLOGY Nature aging Pub Date : 2024-12-13 DOI:10.1038/s43587-024-00721-0
Anna Sophie Lebech Kjaer, Maria Linander Vestager, Rikke Beck Jensen, Anja Pinborg
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Abstract

As fertility rates decline and childbearing age increases globally, assisted reproductive technology (ART) has a crucial role in enhancing birth rates and will contribute substantially to future generations. ART has fulfilled family formation wishes for many individuals facing infertility and aids in solving demographic challenges. Today, up to 9% of the European population is conceived after ART. Considerable advancements in ARTs have improved the effectiveness of treatment, but the ultimate quality control in ART is healthy offspring. Therefore, it is of utmost importance to monitor the health of individuals conceived through ART, and ensure that ART not only provides for the birth of healthy children but also for health into old age.

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随着全球生育率的下降和生育年龄的增加,辅助生殖技术(ART)在提高出生率方面发挥着至关重要的作用,并将为子孙后代做出巨大贡献。辅助生殖技术满足了许多不孕不育患者组建家庭的愿望,有助于解决人口问题。如今,多达 9% 的欧洲人口是通过抗逆转录病毒疗法受孕的。抗逆转录病毒疗法的巨大进步提高了治疗效果,但抗逆转录病毒疗法的最终质量控制是健康的后代。因此,最重要的是监测通过抗逆转录病毒疗法受孕的个体的健康状况,确保抗逆转录病毒疗法不仅能孕育健康的孩子,还能让他们健康地度过晚年。
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Genetics of female and male reproductive traits and their relationship with health, longevity and consequences for offspring Supporting the sexual healthcare needs of aging women Hallmarks of female reproductive aging in physiologic aging mice Healthy aging in individuals born after assisted reproductive technology is a research area for the future Reproductive aging research as a gateway to health and wellbeing
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