Intravenous Magnesium Sulfate as an Adjunct to Intravenous Ketamine for Acute Pain: A Case Series.

Nathan Smith, Sanny Juresic, Kia Lor, Carrie Schmidt, Annie Bell Howrigon, Oludare Olatoye
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Abstract

Intravenous (IV) magnesium sulfate, a versatile electrolyte, plays a pivotal role across various medical domains. From cardiac care to obstetrics, gastrointestinal to pulmonary therapies, the impact is far-reaching among acute care services. Notably, in the postoperative phase of care, it shares intriguing similarities with ketamine as an NMDA receptor antagonist. This case series describes the difficulties experienced with postoperative analgesia in three patient cases with complex comorbidities and discusses the beneficial impact observed when magnesium was administered concomitantly with ketamine. Further research is necessary to outline the specific role, ideal population, and recommended bolus and infusion rate for optimal analgesic efficacy.

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静脉注射硫酸镁辅助静脉注射氯胺酮治疗急性疼痛:一个病例系列。
静脉注射硫酸镁是一种多功能电解质,在各个医疗领域都发挥着举足轻重的作用。从心脏护理到产科,从胃肠道治疗到肺部治疗,它对急症护理服务的影响是深远的。值得注意的是,在术后护理阶段,氯胺酮作为一种 NMDA 受体拮抗剂,与氯胺酮有着惊人的相似之处。本系列病例描述了三例合并症复杂的患者在术后镇痛中遇到的困难,并讨论了在氯胺酮同时使用镁时观察到的有益影响。有必要开展进一步研究,以概述镁的具体作用、理想人群、推荐的栓剂和输注速度,从而达到最佳镇痛效果。
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CiteScore
1.60
自引率
9.10%
发文量
40
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