Rationale for osteoporosis screening in men.

IF 5.4 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM Osteoporosis International Pub Date : 2025-02-01 Epub Date: 2024-12-13 DOI:10.1007/s00198-024-07337-5
Radhika R Narla, Robert A Adler
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Abstract

The US Preventive Services Task Force has not recommended osteoporosis screening in men. Department of Veterans Affairs clinicians reviewed the literature on male osteoporosis screening and treatment. They concluded that targeted screening identifies men at risk and osteoporosis drugs reduce fracture risk similarly in men and women.

Purpose/introduction: The US Preventive Services Task Force (USPSTF) has found insufficient evidence for recommending for or against osteoporosis screening in men. Department of Veterans Affairs osteoporosis experts reviewed the literature on osteoporosis screening and treatment in men.

Methods: Although not done systematically, the literature was reviewed by a panel of 20 Department of Veterans Affairs clinicians with extensive experience with osteoporosis in men. Virtual meetings and multiple email communications resulted in a consensus.

Results: Screening, particularly targeted screening in men, has been found to identify men at risk for fracture. Prior studies have shown osteoporosis drugs have similar effects in men and women. A recent large observational trial demonstrated that hip fracture risk is similarly reduced for both sexes by current medications.

Conclusion: The consensus of the panel was that targeted screening of men for osteoporosis would lead to greater use of osteoporosis medication, lowering fracture risk.

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男性骨质疏松筛查的基本原理。
美国预防服务工作组不建议对男性进行骨质疏松筛查。退伍军人事务部的临床医生回顾了关于男性骨质疏松症筛查和治疗的文献。他们得出的结论是,有针对性的筛查可以识别有风险的男性,骨质疏松症药物降低男性和女性骨折风险的效果相似。目的/介绍:美国预防服务工作组(USPSTF)发现推荐或反对男性骨质疏松筛查的证据不足。退伍军人事务部骨质疏松症专家回顾了关于男性骨质疏松症筛查和治疗的文献。方法:虽然没有系统地完成,但由20名退伍军人事务部临床医生组成的小组对男性骨质疏松症进行了综述。虚拟会议和多封电子邮件沟通达成了共识。结果:筛查,特别是针对男性的筛查,已被发现可以识别有骨折风险的男性。先前的研究表明,治疗骨质疏松的药物对男性和女性有相似的效果。最近的一项大型观察性试验表明,通过目前的药物治疗,男女患者髋部骨折的风险都有相似的降低。结论:专家组的共识是,对男性骨质疏松症进行有针对性的筛查将导致骨质疏松症药物的更多使用,降低骨折风险。
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来源期刊
Osteoporosis International
Osteoporosis International 医学-内分泌学与代谢
CiteScore
8.10
自引率
10.00%
发文量
224
审稿时长
3 months
期刊介绍: An international multi-disciplinary journal which is a joint initiative between the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA, Osteoporosis International provides a forum for the communication and exchange of current ideas concerning the diagnosis, prevention, treatment and management of osteoporosis and other metabolic bone diseases. It publishes: original papers - reporting progress and results in all areas of osteoporosis and its related fields; review articles - reflecting the present state of knowledge in special areas of summarizing limited themes in which discussion has led to clearly defined conclusions; educational articles - giving information on the progress of a topic of particular interest; case reports - of uncommon or interesting presentations of the condition. While focusing on clinical research, the Journal will also accept submissions on more basic aspects of research, where they are considered by the editors to be relevant to the human disease spectrum.
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