Acute Fatty Liver of Pregnancy: Incidence and Clinical Evolution in Toluca, Mexico.

IF 0.3 Puerto Rico health sciences journal Pub Date : 2024-12-01
José Meneses-Calderón, Jazmin Meneses-Figueroa, Jesús Carlos Briones-Garduño, María José Vargas-Contreras, Cecilia Veneranda Contreras-Herrera, Hugo Mendieta-Zerón
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Abstract

Objective: The objective of this study was to determine the incidence and evolution of patients with acute fatty liver of pregnancy (AFLP) over a period of 18 years in the city of Toluca, Mexico.

Methods: This was a descriptive and retrospective study of eighteen years. All women with AFLP confirmed by biopsy were included and the incidence, laboratory test values and complications were registered.

Results: AFLP incidence was of 1 case for every 8,451 deliveries. The main complications were bleeding, infections and neurological compromise. The mortality was of 33.33%.

Conclusion: It can be concluded that AFLP has a slightly lower incidence in Mexico than that reported in other countries but with a higher survival. This condition deserves a multidisciplinary team to improve the survival rate.

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妊娠期急性脂肪肝:墨西哥托卢卡的发病率和临床演变。
目的:本研究的目的是确定18年来墨西哥托卢卡市急性妊娠脂肪肝(AFLP)患者的发病率和演变。方法:这是一项为期18年的描述性和回顾性研究。所有经活检证实为AFLP的女性均被纳入,并记录发生率、实验室检查值和并发症。结果:AFLP发生率为1例/ 8,451次分娩。主要并发症为出血、感染和神经系统损害。死亡率为33.33%。结论:AFLP在墨西哥的发病率略低于其他国家,但生存率较高。这种情况需要一个多学科的团队来提高生存率。
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