Allograft versus autograft ACL reconstruction in skeletally immature patients: a systematic review.

IF 6.7 2区医学 Q1 Medicine British medical bulletin Pub Date : 2024-12-05 DOI:10.1093/bmb/ldae020

Filippo Migliorini, Marco Pilone, Luise Schäfer, Francesca Alzira Bertini, Riccardo Giorgino, Nicola Maffulli

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Abstract

Introduction: Anterior cruciate ligament (ACL) injuries in children and adolescents with open physes are common.

Areas of agreement: Evidence of ACL reconstruction using allografts in children with open physes is limited.

Areas of controversy: Whether the outcomes of ACL allograft reconstruction in children and adolescents with open physes are superior to autograft ACL reconstruction is unclear, with contrasting evidence.

Source of data: In October 2024, the Web of Science, PubMed, and Embase were accessed with no additional filters. Only clinical investigations evaluating ACL reconstruction in children or adolescents with open physes were eligible. Only studies reporting a minimum length of 24 months of follow-up were included.

Areas timely for developing research: Children who undergo allograft ACL reconstruction demonstrate similar functional outcomes to those who undergo autograft ACL reconstruction. Although allografts allow a faster return to sport, the greater laxity, the reduced activity level, and the higher failure and reoperation rates make their use dubious as a first-choice option for ACL reconstruction in skeletally immature patients.

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骨骼不成熟患者的同种异体移植与自体移植前交叉韧带重建：系统性综述。

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来源期刊

British medical bulletin 医学-医学：内科

CiteScore

13.10

自引率

1.50%

发文量

审稿时长

>12 weeks

期刊介绍： British Medical Bulletin is a multidisciplinary publication, which comprises high quality reviews aimed at generalist physicians, junior doctors, and medical students in both developed and developing countries. Its key aims are to provide interpretations of growing points in medicine by trusted experts in the field, and to assist practitioners in incorporating not just evidence but new conceptual ways of thinking into their practice.