EXPRESS: Synergistic Efficacy of Orthokeratology and 0.01% Atropine in Controlling Pediatric Myopia Progression: A Retrospective Analysis.

IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Journal of Investigative Medicine Pub Date : 2024-12-16 DOI:10.1177/10815589241308819
Yingying Yang, Zhigang Xiao, Jing Ouyang, Yan Guo
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Abstract

This study investigates the combined efficacy of orthokeratology lenses and 0.01% atropine in controlling the progression of pediatric myopia. The study, conducted retrospectively on 33 children aged 8-14, measured key parameters, including axial length growth, uncorrected visual acuity (UCVA), intraocular pressure (IOP), tear film breakup time (TBUT), and pupil diameter. The results revealed a significant reduction in axial length growth with the combined treatment compared to orthokeratology alone, while UCVA and IOP remained stable. TBUT decreased, and pupil diameter increased post-treatment. The findings suggest that combining orthokeratology with low-dose atropine offers a safe and effective strategy for managing pediatric myopia, particularly in younger patients.

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这项研究调查了角膜塑形镜和 0.01% 阿托品在控制小儿近视发展方面的综合疗效。该研究对 33 名 8-14 岁的儿童进行了回顾性研究,测量了包括轴长增长、未矫正视力 (UCVA)、眼压 (IOP)、泪膜破裂时间 (TBUT) 和瞳孔直径在内的关键参数。结果显示,与单独使用角膜矫形术相比,联合治疗可显著减少轴长增长,而 UCVA 和 IOP 保持稳定。治疗后TBUT下降,瞳孔直径增加。研究结果表明,将角膜矫形术与小剂量阿托品结合使用,是一种安全有效的治疗小儿近视的方法,尤其适用于年龄较小的患者。
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来源期刊
Journal of Investigative Medicine
Journal of Investigative Medicine 医学-医学:内科
CiteScore
4.90
自引率
0.00%
发文量
111
审稿时长
24 months
期刊介绍: Journal of Investigative Medicine (JIM) is the official publication of the American Federation for Medical Research. The journal is peer-reviewed and publishes high-quality original articles and reviews in the areas of basic, clinical, and translational medical research. JIM publishes on all topics and specialty areas that are critical to the conduct of the entire spectrum of biomedical research: from the translation of clinical observations at the bedside, to basic and animal research to clinical research and the implementation of innovative medical care.
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