Short-Term Endotamponade With Perfluorocarbon Liquids for Giant Retinal Tear-Associated Retinal Detachment.

IF 0.5 Q4 OPHTHALMOLOGY Journal of VitreoRetinal Diseases Pub Date : 2024-12-13 DOI:10.1177/24741264241305105
Naresh Babu Kannan, MuthuKrishnan Vallinayagam, Tanya Balakrishnan, Avik Dey Sarkar, Renu P Rajan, Kim Ramasamy
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Abstract

Purpose: To investigate the use of short-term postoperative endotamponade with perfluorocarbon liquids (PFCLs) for the treatment of giant retinal tear-associated rhegmatogenous retinal detachment (RRD). Methods: This retrospective study evaluated patients who had 2-stage surgery, which entailed pars plana vitrectomy (PPV) completed in 2 consecutive surgeries spaced 5 days apart, during which a short-term tamponade with PFCL was used (Group 1), and patients who had conventional single-stage PPV with long-term silicone oil (SO) tamponade (Group 2). Results: The study comprised 74 eyes of 68 patients, 52 in Group 1 and 22 in Group 2. The mean (±SD) patient age at presentation was 48.19 ± 15.73 years. Of the cases, 18.9% had high myopia and 13.5% had previous trauma. The improvement in best-corrected visual acuity (BCVA) was significantly better in Group 1 than in Group 2 at all postoperative visits (P = .004, postoperative day [POD] 15; P = .002, POD 90; P = .00006, final follow-up). Anatomic success (an attached retina) was achieved in 82.7% of patients in Group 1 and in 72.7% of patients in Group 2 (P = .33). At the 6-month postoperative follow-up, 54.5% of patients and 50% of patients, respectively, had a logMAR BCVA of 1.00 or better (P = .721). The mean change in intraocular pressure from baseline was statistically significant in both groups (Group 1, P = .012; Group 2, P = .018). Conclusions: Anatomic and functional outcomes in giant retinal tear-associated RRD can be improved with short-term postoperative endotamponade with PFCLs.

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目的:研究用全氟碳化物液体(PFCL)进行术后短期内膜填塞治疗巨大视网膜撕裂相关流变性视网膜脱离(RRD)的方法。方法:这项回顾性研究评估了接受两期手术的患者(第一组)和接受传统单期PPV手术并长期使用硅油(SO)填塞的患者(第二组),前者需要在两次连续手术中完成玻璃体旁切除术(PPV),手术间隔为5天。研究结果研究包括 68 名患者的 74 只眼睛,第一组 52 例,第二组 22 例。患者的平均(±SD)年龄为 48.19 ± 15.73 岁。其中,18.9%的患者患有高度近视,13.5%的患者曾受过外伤。在所有术后随访中,第一组患者的最佳矫正视力(BCVA)改善情况均明显优于第二组(术后第15天,P = .004;术后第90天,P = .002;最终随访,P = .00006)。第一组 82.7% 的患者和第二组 72.7% 的患者都取得了解剖成功(视网膜附着)(P = .33)。在术后 6 个月的随访中,分别有 54.5% 和 50% 的患者的 BCVA 对数达到或优于 1.00(P = .721)。与基线相比,两组患者的平均眼压变化均有统计学意义(第一组,P = .012;第二组,P = .018)。结论巨型视网膜撕裂相关 RRD 的解剖和功能结果可通过术后短期使用 PFCL 进行内膜填塞得到改善。
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