An Epidemiological Study on Magnitude of Selected Components of Metabolic Syndrome and Its Risk Factors among First-year MBBS Students.

Arkaprava Dasgupta, Kakali Das Sarkar, Adwitiya Das
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Abstract

Background: Previous research has suggested that the prevalence of risk factors for cardiometabolic diseases is higher in South Asians, with premature presentation common in this subpopulation.

Aim: To explore this further, we assessed the prevalence of metabolic syndrome (MetS) components and risk factors among young adults.

Methods: This was a cross-sectional, epidemiological, institution-based study conducted at the Medical College in Eastern India. The study aimed to assess the demographic, physical, and biochemical risk factors for MetS among first-year medical students using a predesigned, pretested, semistructured questionnaire. The relationship between socio-demographics and other characteristics of MetS was calculated by using Chi-squared tests and unpaired t-tests. A p-value ≤ 0.05 was significant with a 95% confidence interval (CI). The logistic regression method was applied to find out the strength of the association of sociodemographics and other characteristics with MetS.

Results: The study included 150 first-year medical undergraduate students (mean age of 18.5 ± 0.4 years), comprising 68% males. Among students who were smokers, consumed alcohol, and had excessive junk food, salt, and red meat, the risk of MetS was significantly greater (p < 0.00001). The logistic regression revealed that history of smoking [adjusted odds ratio (AOR) 5.32, 95% CI (3.31-9.02)] and history of alcohol intake [AOR 6.23, 95% CI (2.45-8.62)] were significantly associated with greater odds of MetS.

Conclusion: In young adults, the risk of premature cardiovascular disease can be reduced by focusing on the early identification and prevention of risk factors for MetS. Context-specific, cost-effective, and feasible interventions to reduce identified risk factors are the need of the hour.

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MBBS一年级学生代谢综合征部分成分及其危险因素的流行病学研究。
背景:先前的研究表明,南亚人心脏代谢疾病的危险因素患病率较高,在这一亚人群中出现过早的症状很常见。目的:为了进一步探讨这一点,我们评估了年轻人中代谢综合征(MetS)成分和危险因素的患病率。方法:这是一项在东印度医学院进行的横断面、流行病学、基于机构的研究。本研究旨在使用预先设计、预先测试、半结构化的问卷,评估医一年级学生发生MetS的人口学、物理和生化危险因素。社会人口统计学与MetS其他特征之间的关系通过卡方检验和非配对t检验来计算。p值≤0.05为显著性,95%置信区间(CI)。采用logistic回归方法,找出社会人口统计学和其他特征与MetS的关联强度。结果:本研究纳入150名医学本科一年级学生,平均年龄18.5±0.4岁,其中68%为男性。在吸烟、饮酒、过量食用垃圾食品、盐和红肉的学生中,met的风险明显更高(p < 0.00001)。logistic回归分析显示,吸烟史[调整比值比(AOR) 5.32, 95% CI(3.31-9.02)]和饮酒史[调整比值比(AOR) 6.23, 95% CI(2.45-8.62)]与MetS的高发生率显著相关。结论:在年轻人中,通过早期识别和预防MetS的危险因素,可以降低早发心血管疾病的风险。当前需要的是针对具体情况、具有成本效益和可行的干预措施,以减少已确定的风险因素。
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