Intact fish skin graft a new hope for the treatment of diabetic foot ulcers: A case report.

IF 4.2 3区医学 Q1 ENDOCRINOLOGY & METABOLISM World Journal of Diabetes Pub Date : 2024-12-15 DOI:10.4239/wjd.v15.i12.2353

Anne Christine Jugnet, Tatiana Benard, Corinne Lequint, Elise Bobony, Anna-Rosiana Pieheiro, Thomas Winther, Alfred Penfornis, Dured Dardari

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Abstract

Background: Diabetic foot ulcers (DFUs) are a real public health problem which carry a high risk of amputation. The treatment of DFUs is based on general management such as the treatment of infection, arterial disease, and offloading, but recent studies have shown that the quality of the local covering can impact the healing rate.

Case summary: We report the case of a 39-year-old man, living with diabetes since the age of 15, who developed DFU on the dorsum of his left foot, with muscle and tendon involvement. Conventional management with intensive diabetes control, surgery, treatment of infection and negative pressure therapy gave only limited results. The patient benefited from the application of an intact fish skin graft with complete epithelialisation of the ulcer after 10 weeks of treatment.

Conclusion: The use of intact fish skin graft appears to be a promising option for deep DFUs.

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完整鱼皮移植治疗糖尿病足溃疡的新希望：1例报告。

背景：糖尿病足溃疡（DFUs）是一个真正的公共卫生问题，具有很高的截肢风险。DFUs的治疗基于一般管理，如感染、动脉疾病和卸载的治疗，但最近的研究表明，局部覆盖的质量会影响治愈率。病例总结：我们报告一名39岁的男性，自15岁以来一直患有糖尿病，他在左脚背发展为DFU，并累及肌肉和肌腱。常规的糖尿病控制、手术、感染治疗和负压治疗效果有限。治疗10周后，患者受益于完整鱼皮移植，溃疡完全上皮化。结论：采用完整鱼皮移植治疗深部dfu是一种很有前途的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Diabetes ENDOCRINOLOGY & METABOLISM-

自引率

2.40%

发文量

909

期刊介绍： The WJD is a high-quality, peer reviewed, open-access journal. The primary task of WJD is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of diabetes. In order to promote productive academic communication, the peer review process for the WJD is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJD are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in diabetes. Scope: Diabetes Complications, Experimental Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes, Gestational, Diabetic Angiopathies, Diabetic Cardiomyopathies, Diabetic Coma, Diabetic Ketoacidosis, Diabetic Nephropathies, Diabetic Neuropathies, Donohue Syndrome, Fetal Macrosomia, and Prediabetic State.