Televisits for patients with atopic dermatitis treated with dupilumab: experience from a tertiary care center in Northern Italy.

IF 1.8 4区 医学 Q3 DERMATOLOGY Italian Journal of Dermatology and Venereology Pub Date : 2024-12-01 Epub Date: 2024-12-17 DOI:10.23736/S2784-8671.24.07974-X
Luca Mastorino, Gitana Scozzari, Simone Ribero, Pietro Quaglino, Antonio Scarmozzino, Michela Ortoncelli
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Abstract

Background: Atopic dermatitis (AD) is an inflammatory skin disease. The monoclonal antibody dupilumab can provide a rapid response with achievement of stable clinical disease. This study aimed to confirm the effectiveness of a televisit approach for patients with AD and treated with dupilumab.

Methods: Demographic data and characteristics at baseline including mean EASI, mean NRSp, mean DLQI, and mean NRSds were retrospectively assessed and subsequently collected at up to 48 weeks, last visit in attendance, and up to the fourth televisit. The mean reduction of the above scores, and achievement at each time point of EASI≤7, EASI 75, EASI 90, DLQI 0/1, and NRSp≤4 were considered as endpoints.

Results: Twelve patients underwent at least 1 televisit. The mean follow-up on dupilumab before switching to a televisit was 28.5 months. The mean EASI at the last face-to-face visit was 0.75 and remained stable at subsequent televisit visits. All patients achieved EASI≤7 as early as week 16 which was during the televisits. A similar trend was seen for EASI 75. Only 1 patient discontinued the televisits after 2 visits, preferring to return in person.

Conclusions: In our case series of remotely-followed patients, clinical and patient-reported outcomes remained stable.

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为接受杜匹单抗治疗的特应性皮炎患者提供电视诊疗:意大利北部一家三级医疗中心的经验。
背景:特应性皮炎(AD)是一种炎症性皮肤病。单克隆抗体dupilumab可以提供快速反应,实现临床疾病的稳定。本研究旨在证实电视访视方法对dupilumab治疗的AD患者的有效性。方法:回顾性评估人口统计学数据和基线特征,包括平均EASI、平均NRSp、平均DLQI和平均nrsd,并随后在48周、最后一次就诊和第四次电视就诊时收集这些数据。以上述评分的平均降幅,以及EASI≤7、EASI 75、EASI 90、DLQI 0/1、NRSp≤4各时间点的实现情况为终点。结果:12例患者至少进行了1次电视检查。在转为电视治疗之前,dupilumab的平均随访时间为28.5个月。最后一次面对面访问时的平均EASI为0.75,在随后的电视访问中保持稳定。所有患者早在第16周即电视访问期间就达到EASI≤7。easi75也出现了类似的趋势。只有1名患者在两次就诊后停止了电视检查,更愿意亲自返回。结论:在我们的远程随访患者病例系列中,临床和患者报告的结果保持稳定。
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CiteScore
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442
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