Review of Emotion Regulation in Late Life Mood Disorders.

Journal of psychiatry and brain science Pub Date : 2024-01-01 Epub Date: 2024-11-22 DOI:10.20900/jpbs.20240008
Regan E Patrick, Rebecca A Dickinson, Allison Gregg, Jack R Kaufman, Jeremy Maciarz, Julia G Merrill, Loreal A Williams, Sara L Weisenbach
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Abstract

Emotion regulation (ER), or the ability to modulate the experience and expression of emotion, is critical to adaptive functioning and is a key feature of mood disorders. At the same time, normal aging is associated with changes in ER, though the interaction of aging with the presence of a mood disorder are unclear. Here, we review what is known about ER and its underlying neural mechanisms in late life mood disorders, specifically late life depression and bipolar disorder. We also review behavioral and neuromodulation therapies that seek to reduce negative affect and improve positive affect. We conclude with recommendations for future research into the nature and mechanisms of ER and interventions targeting ER in older adults with mood disorders.

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晚年情绪障碍的情绪调节研究综述。
情绪调节(ER),或调节情绪体验和表达的能力,对适应性功能至关重要,是情绪障碍的一个关键特征。与此同时,正常的衰老与内质网的变化有关,尽管衰老与情绪障碍的存在之间的相互作用尚不清楚。在这里,我们回顾了已知的ER及其在晚年情绪障碍,特别是晚年抑郁症和双相情感障碍中的潜在神经机制。我们还回顾了寻求减少消极影响和改善积极影响的行为和神经调节疗法。最后,我们对未来研究雌激素受体的性质和机制以及针对老年情绪障碍患者雌激素受体的干预措施提出了建议。
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