Mineral Supplements in Ageing.

Q1 Biochemistry, Genetics and Molecular Biology Sub-cellular biochemistry Pub Date : 2024-01-01 DOI:10.1007/978-3-031-66768-8_13
Simon Welham, Peter Rose, Charlotte Kirk, Lisa Coneyworth, Amanda Avery
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Abstract

With advancing age, achievement of dietary adequacy for all nutrients is increasingly difficult and this is particularly so for minerals. Various factors impede mineral acquisition and absorption including reduced appetite, depressed gastric acid production and dysregulation across a range of signalling pathways in the intestinal mucosa. Minerals are required in sufficient levels since they are critical for the proper functioning of metabolic processes in cells and tissues, including energy metabolism, DNA and protein synthesis, immune function, mobility, and skeletal integrity. When uptake is diminished or loss exceeds absorption, alternative approaches are required to enable individuals to maintain adequate mineral levels. Currently, supplementation has been used effectively in populations for the restoration of levels of some minerals like iron, zinc, and calcium, but these may not be without inherent challenges. Therefore, in this chapter we review the current understanding around the effectiveness of mineral supplementation for the minerals most clinically relevant for the elderly.

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矿物质补充剂对衰老的影响。
随着年龄的增长,实现饮食中所有营养素的充足性越来越困难,矿物质尤其如此。多种因素阻碍矿物质的获取和吸收,包括食欲下降、胃酸产生抑制和肠粘膜一系列信号通路失调。人体需要足够的矿物质,因为它们对细胞和组织中代谢过程的正常运作至关重要,包括能量代谢、DNA和蛋白质合成、免疫功能、活动性和骨骼完整性。当摄取减少或流失超过吸收时,需要其他方法使个人保持足够的矿物质水平。目前,补充剂已被有效地用于人群中恢复一些矿物质的水平,如铁、锌和钙,但这些可能不是没有固有的挑战。因此,在本章中,我们回顾了目前对矿物质补充对老年人最有临床意义的矿物质的有效性的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Sub-cellular biochemistry
Sub-cellular biochemistry Biochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
5.90
自引率
0.00%
发文量
33
期刊介绍: The book series SUBCELLULAR BIOCHEMISTRY is a renowned and well recognized forum for disseminating advances of emerging topics in Cell Biology and related subjects. All volumes are edited by established scientists and the individual chapters are written by experts on the relevant topic. The individual chapters of each volume are fully citable and indexed in Medline/Pubmed to ensure maximum visibility of the work.
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