Correlation between histopathology properties of dartos tissue and the severity of penile curvature in hypospadias.

IF 1.4 Q3 UROLOGY & NEPHROLOGY Archivio Italiano di Urologia e Andrologia Pub Date : 2024-12-18 DOI:10.4081/aiua.2024.12894

Gede Wirya Kusuma Duarsa, Pande Made Wisnu Tirtayasa, Ni Wayan Winarti, Andy Michael, Komang Harsa Abhinaya Duarsa

{"title":"Correlation between histopathology properties of dartos tissue and the severity of penile curvature in hypospadias.","authors":"Gede Wirya Kusuma Duarsa, Pande Made Wisnu Tirtayasa, Ni Wayan Winarti, Andy Michael, Komang Harsa Abhinaya Duarsa","doi":"10.4081/aiua.2024.12894","DOIUrl":null,"url":null,"abstract":"Purpose: Hypospadias, one of the congenital anomalies commonly associated with some degrees of ventral penile curvature that may arise from malformation of dartos fascia, the chordee. Our study aims to determine the correlation between the histopathology properties of dartos fascia and the severity of ventral penile curvature in hypospadias.Materials and methods: One hundred hypospadias patients with various degrees of ventral penile curvature were included in this cross-sectional analytical study from 2020 to 2022. During hypospadias repair, ventral dartos fascia was excised and analyzed for the degree of collagen thickness and the severity of the fibrotic condition.Results: Out of 100 patients, the mean age was 6.58 + 4.28 years, who were classified as mild to moderate (66%) and severe (34%) ventral curvature cases. The analyses showed significant differences in the severity of fibrotic condition and collagen thickness of dartos fascia to the severity of penile ventral curvature with p-values of 0.002 and 0.017, respectively.Conclusions: The difference in histopathology properties of dartos fascia may affect the severity of penile curvature in hypospadias patients.","PeriodicalId":46900,"journal":{"name":"Archivio Italiano di Urologia e Andrologia","volume":"96 4","pages":"12894"},"PeriodicalIF":1.4000,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivio Italiano di Urologia e Andrologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/aiua.2024.12894","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: Hypospadias, one of the congenital anomalies commonly associated with some degrees of ventral penile curvature that may arise from malformation of dartos fascia, the chordee. Our study aims to determine the correlation between the histopathology properties of dartos fascia and the severity of ventral penile curvature in hypospadias.

Materials and methods: One hundred hypospadias patients with various degrees of ventral penile curvature were included in this cross-sectional analytical study from 2020 to 2022. During hypospadias repair, ventral dartos fascia was excised and analyzed for the degree of collagen thickness and the severity of the fibrotic condition.

Results: Out of 100 patients, the mean age was 6.58 + 4.28 years, who were classified as mild to moderate (66%) and severe (34%) ventral curvature cases. The analyses showed significant differences in the severity of fibrotic condition and collagen thickness of dartos fascia to the severity of penile ventral curvature with p-values of 0.002 and 0.017, respectively.

Conclusions: The difference in histopathology properties of dartos fascia may affect the severity of penile curvature in hypospadias patients.

查看原文