Fluctuations of Anterior Chamber Depth and Astigmatism in Pseudophakic Eyes.

Clinical ophthalmology (Auckland, N.Z.) Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI:10.2147/OPTH.S492253
Larysa Tutchenko, Sudi Patel, Mykhailo Skovron, Oleksiy V Voytsekhivskyy, Fanka Gilevska
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Abstract

Purpose: To explore the significance of changes in anterior chamber depth (ΔACD) and astigmatism between 4 and 8 weeks following uneventful phacoemulsification.

Patients and methods: Anterior chamber depth (ACD, mm), autorefractometry and subjective refraction were monitored in pseudophakic eyes implanted with non-toric IOLs (group 1, SA60AT, n=36; group 2, SN60WF, n=34; group 3, ICBOO, n=16) and phakic control group (n=30, group 4a, for ACD and autorefractometry) over four weeks. Changes in subjective refractions were compared with repeatability in normal phakic eyes (n=30, group 4b).

Results: Reporting key results (p<0.01), mean (±sd 95% CI) ΔACD values (ACD at start minus ACD at four weeks) were +0.02 (±0.37, -0.16 to 0.08), +0.22 (±0.51,0.05 to 0.39), -0.33 (±0.51, -0.58 to -0.08), -0.02 (±0.07, -0.04 to 0.01) in groups 1-4a respectively. Differences were significant (1-way ANOVA, F=7.02). Pooling data from the pseudophakic eyes (n=86) induced astigmatism (IA) by autorefractometry was significantly greater in comparison with group 4a [-0.78D (±0.67, -0.92 to -0.64) and -0.19D (±0.16, -0.25 to - 0.13)]. IA power correlated with the initial power of refractive astigmatism at 4 weeks (A), [IA = 0.36A-0.30 (r2=0.207) and IA = 0.39A-0.29 (r2=0.232) by autorefractometry and subjective refraction, respectively]. In groups 1-3, vector analysis revealed i) the change in refraction in over 55% of eyes was beyond the 95% confidence interval limits observed in groups 4a and 4b, ii) some significant associations between changes in vectors describing astigmatism with ΔACD and IOL labelled power.

Conclusion: Changes in ACD and refraction still occur four weeks after unremarkable phacoemulsification and the inter-relationship depends on IOL design/type. Other factors, such as tilt or dislocation of the IOL along the X-Y axes parallel to Listing's plane, accompanying changes in ACD are expected to affect the postop astigmatism.

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假性散光眼前房深度和散光的波动。
目的:探讨超声乳化术术后4 ~ 8周前房深度(ΔACD)和散光变化的意义。患者和方法:观察人工晶状体植入假晶状眼的前房深度(ACD, mm)、自体屈光和主观屈光(1组,SA60AT, n=36;2组SN60WF, n=34;第3组,ICBOO组,n=16)和晶状体对照组(n=30, 4a组,用于ACD和自动折射),为期四周。将主观屈光的变化与正常晶状眼的可重复性进行比较(n=30, 4b组)。结果:报告的关键结果(p2=0.207)和IA = 0.39A-0.29 (r2=0.232)分别由自动折射和主观折射]。在1-3组中,矢量分析显示i)超过55%的眼睛的屈光变化超出了4a组和4b组观察到的95%置信区间限制,ii) ΔACD描述散光的矢量变化与IOL标记度数之间存在显著关联。结论:超声乳化术后4周内ACD和屈光仍有变化,其变化与人工晶状体设计/类型有关。其他因素,如IOL沿平行于李氏平面的X-Y轴的倾斜或脱位,以及伴随的ACD变化,预计会影响眼后散光。
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