PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome

IF 12.8 1区 医学 Q1 HEMATOLOGY Leukemia Pub Date : 2024-12-19 DOI:10.1038/s41375-024-02502-5
Aurélie Caye-Eude, Grazia Fazio, Agata Pastorczak, Judith M. Boer, Doris Steinemann, Debdutta Ganguli, Edwin Sonneveld, Sabrina Haslinger, Lucía D’Andrea, Jutta Bradtke, Bruno A. Lopes, Marketa Zaliova, Gabriele Escherich, Margit König, Klaus Fortschegger, Andrea Inthal, Irina Stasevich, Mariana Emerenciano, Jan Trka, Luis Castillo, Mayur Parihar, Anthony V. Moorman, Anke K. Bergmann, Monique L. den Boer, Wojciech Młynarski, Giovanni Cazzaniga, Hélène Cavé, Karin Nebral, Dagmar Schinnerl, Sabine Strehl
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PAX5::AUTS2儿童B-ALL:一种易复发的遗传亚型,常累及中枢神经系统,预后较差
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来源期刊
Leukemia
Leukemia 医学-血液学
CiteScore
18.10
自引率
3.50%
发文量
270
审稿时长
3-6 weeks
期刊介绍: Title: Leukemia Journal Overview: Publishes high-quality, peer-reviewed research Covers all aspects of research and treatment of leukemia and allied diseases Includes studies of normal hemopoiesis due to comparative relevance Topics of Interest: Oncogenes Growth factors Stem cells Leukemia genomics Cell cycle Signal transduction Molecular targets for therapy And more Content Types: Original research articles Reviews Letters Correspondence Comments elaborating on significant advances and covering topical issues
期刊最新文献
Correspondence to: “Combination therapies with ponatinib and asciminib in a preclinical model of chronic myeloid leukemia blast crisis with compound mutations”, Curik N et al. Leukemia. 2024; 38: 1415–1418 VDAC2 primes myeloma cells for BAK-dependent apoptosis and represents a novel therapeutic target STAT6 mutations compensate for CREBBP mutations and hyperactivate IL4/STAT6/RRAGD/mTOR signaling in follicular lymphoma Phase 1 clinical trial of B-Cell Maturation Antigen (BCMA) NEX-T® Chimeric Antigen Receptor (CAR) T cell therapy CC-98633/BMS-986354 in participants with triple-class exposed multiple myeloma Patterns and variations of copy number alterations in acute myeloid leukemia: insights from the LeukAtlas database
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