Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain
Benjamin P. Readhead, Diego F. Mastroeni, Qi Wang, Maria A. Sierra, Camila de Ávila, Tajudeen O. Jimoh, Jean-Vianney Haure-Mirande, Kristina E. Atanasoff, Jennifer Nolz, Crystal Suazo, Nathaniel J. Barton, Adrian R. Orszulak, Samantha M. Chigas, Khanh Tran, Anne Mirza, Krista Ryon, Jacqueline Proszynski, Deena Najjar, Joel T. Dudley, Sean T. H. Liu, Sam Gandy, Michelle E. Ehrlich, Eric Alsop, Jerry Antone, Rebecca Reiman, Cory Funk, Rebecca L. Best, Michael Jhatro, Kathy Kamath, John Shon, Timothy F. Kowalik, David A. Bennett, Winnie S. Liang, Geidy E. Serrano, Thomas G. Beach, Kendall Van Keuren-Jensen, Christopher E. Mason, Yingleong Chan, Elaine T. Lim, Domenico Tortorella, Eric M. Reiman
{"title":"Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain","authors":"Benjamin P. Readhead, Diego F. Mastroeni, Qi Wang, Maria A. Sierra, Camila de Ávila, Tajudeen O. Jimoh, Jean-Vianney Haure-Mirande, Kristina E. Atanasoff, Jennifer Nolz, Crystal Suazo, Nathaniel J. Barton, Adrian R. Orszulak, Samantha M. Chigas, Khanh Tran, Anne Mirza, Krista Ryon, Jacqueline Proszynski, Deena Najjar, Joel T. Dudley, Sean T. H. Liu, Sam Gandy, Michelle E. Ehrlich, Eric Alsop, Jerry Antone, Rebecca Reiman, Cory Funk, Rebecca L. Best, Michael Jhatro, Kathy Kamath, John Shon, Timothy F. Kowalik, David A. Bennett, Winnie S. Liang, Geidy E. Serrano, Thomas G. Beach, Kendall Van Keuren-Jensen, Christopher E. Mason, Yingleong Chan, Elaine T. Lim, Domenico Tortorella, Eric M. Reiman","doi":"10.1002/alz.14401","DOIUrl":null,"url":null,"abstract":"While there may be microbial contributions to Alzheimer's disease (AD), findings have been inconclusive. We recently reported an AD-associated CD83(+) microglia subtype associated with increased immunoglobulin G4 (IgG4) in the transverse colon (TC).","PeriodicalId":7471,"journal":{"name":"Alzheimer's & Dementia","volume":"25 1","pages":""},"PeriodicalIF":13.0000,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alzheimer's & Dementia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/alz.14401","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
While there may be microbial contributions to Alzheimer's disease (AD), findings have been inconclusive. We recently reported an AD-associated CD83(+) microglia subtype associated with increased immunoglobulin G4 (IgG4) in the transverse colon (TC).
期刊介绍：
Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
