Vaccination for solid organ transplanted patients: Recommendations, efficacy, and safety.

Tsvetelina Velikova, Stavros Gerasoudis, Hristiana Batselova
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Abstract

Solid organ transplant recipients face unique challenges in managing their immunosuppressed status, making vaccination a critical consideration. This review aimed to comprehensively analyze current recommendations, evaluate the efficacy of vaccinations in this population, and assess safety concerns. We explored the latest evidence on vaccine types, timing, and potential benefits for transplant patients, highlighting the importance of individualized approaches for routinely used vaccines as well as coronavirus disease 2019 vaccines. By synthesizing available data, this review underscored the pressing need to optimize vaccination strategies, ensuring that transplant recipients can obtain the full protection against many pathogens while minimizing risks associated with their post-transplant immunosuppression.

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实体器官移植患者的疫苗接种:建议、有效性和安全性。
实体器官移植受者在控制其免疫抑制状态方面面临独特的挑战,因此接种疫苗是一个关键的考虑因素。本综述旨在全面分析目前的建议,评估该人群接种疫苗的有效性,并评估安全性问题。我们探索了关于疫苗类型、时机和移植患者潜在益处的最新证据,强调了常规使用疫苗和2019冠状病毒病疫苗个性化方法的重要性。通过综合现有数据,本综述强调了优化疫苗接种策略的迫切需要,以确保移植受者能够获得针对许多病原体的充分保护,同时将移植后免疫抑制相关的风险降至最低。
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