Case Report: Acute intussusception in a 2-year-old male patient: a rare case of Burkitt's lymphoma coexisting with Meckel's diverticulum.

IF 2.1 3区 医学 Q2 PEDIATRICS Frontiers in Pediatrics Pub Date : 2024-12-05 eCollection Date: 2024-01-01 DOI:10.3389/fped.2024.1489118
Xinggui Fang, Biao Yang, Ming Cao, Xiaodong Xu, Benquan Wang
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Abstract

In children, 90% cases of intussusception are idiopathic and the remaining 10% are attributed to underlying diseases (most commonly due to Meckel's diverticulum, polyps then either duplication cyst or mesentery cysts, and rarely due to Burkitt's lymphoma). The occurrence of acute intestinal intussusception caused by Burkitt's lymphoma in children under the age of 5 is exceedingly rare. Burkitt's lymphoma presents with diverse clinical manifestations, often leading to the identification of an abdominal tumor in pediatric patients. This highly aggressive and rapidly proliferating neoplasm can induce indirect symptoms due to compression or direct involvement of the intestinal lumen, resulting in intussusception. Herein, we present a case report of ileocolic-type intussusception in a 2-year-old boy, which was attributed to the coexistence of Burkitt's lymphoma and Meckel's diverticulum. Notably, this patient exhibited atypical clinical features for Burkitt's lymphoma and did not belong to the high-risk demographic associated with this rare disease. Furthermore, this case represents a unique combination involving the most prevalent cause of Meckel's diverticula and the rarest etiology of Burkitt's lymphoma.

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病例报告:1例2岁男性患者急性肠套叠:一例罕见的伯基特淋巴瘤合并梅克尔憩室。
在儿童中,90% 的肠套叠是特发性的,其余 10%的肠套叠是由潜在疾病引起的(最常见的是梅克尔憩室、息肉,然后是重复囊肿或肠系膜囊肿,很少见的是伯基特淋巴瘤)。在 5 岁以下儿童中,由伯基特淋巴瘤引起的急性肠套叠极为罕见。伯基特淋巴瘤的临床表现多种多样,通常会在儿童患者中发现腹部肿瘤。这种侵袭性强、增殖迅速的肿瘤可因压迫或直接累及肠腔而引起间接症状,导致肠套叠。在此,我们报告了一例两岁男童回结肠型肠套叠的病例,其原因是伯基特淋巴瘤和梅克尔憩室同时存在。值得注意的是,这名患者表现出伯基特淋巴瘤的非典型临床特征,不属于这种罕见疾病的高危人群。此外,该病例是梅克尔憩室最常见病因和伯基特淋巴瘤最罕见病因的独特结合。
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来源期刊
Frontiers in Pediatrics
Frontiers in Pediatrics Medicine-Pediatrics, Perinatology and Child Health
CiteScore
3.60
自引率
7.70%
发文量
2132
审稿时长
14 weeks
期刊介绍: Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.
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