Ning Sun, Rui Wei, Bochao Jia, Taiwei Lou, Zirong Li, Xiaowei Nie, Wenxiao Yu, Miaoran Wang, Qiuyan Li
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引用次数: 0
Abstract
Globally, there are over 3 million severe cases of influenza each year, leading to up to half a million deaths. This study provides a comprehensive analysis of the current status of children's influenza vaccine research over the past 20 years and explores potential future research trends, including improvements in vaccine coverage and strategies to address vaccine hesitancy. We extracted all research data on children's influenza vaccines from 2004 to 2024 using the Web of Science Core Collection (WOSCC). The contributions of various countries/regions, institutions, authors, and journals in this field were assessed, and research hotspots as well as promising future trends were predicted through keyword analysis using CiteSpace and VOSviewer. A total of 2,598 related publications from 2004 to 2024 were identified and collected for analysis. The United States (USA) and England emerged as the leading contributors with the highest number of published papers. AstraZeneca was identified as a key leader among research institutions, and Ambrose Christopher S was recognized as the most productive author in this field. The journals Vaccine and Human Vaccines & Immunotherapeutics stood out as the most prominent publications in this area. The keyword analysis highlighted that international research collaboration maybe a promising strategy for bridging global gaps; Addressing vaccine hesitancy could potentially increase vaccination coverage; Live attenuated vaccines, intranasal administration and universal vaccines are promising directions for future development. These insights highlight potential avenues for improving influenza vaccine coverage and inform strategies to mitigate vaccine hesitancy, crucial for protecting children and enhancing public health.
全球每年有300多万例严重流感病例,导致多达50万人死亡。本研究全面分析了过去20年来儿童流感疫苗研究的现状,并探讨了潜在的未来研究趋势,包括提高疫苗覆盖率和解决疫苗犹豫问题的策略。我们使用Web of Science Core Collection (WOSCC)提取了2004 - 2024年关于儿童流感疫苗的所有研究数据。通过CiteSpace和VOSviewer的关键词分析,评估了各国/地区、机构、作者和期刊在该领域的贡献,预测了该领域的研究热点和未来发展趋势。从2004年到2024年,共收集了2598份相关出版物进行分析。美国(USA)和英国成为发表论文数量最多的主要贡献者。阿斯利康被认为是研究机构中的关键领导者,Ambrose Christopher S被认为是该领域最具生产力的作者。《疫苗》和《人类疫苗与免疫疗法》杂志是这一领域最突出的出版物。关键词分析强调,国际研究合作可能是弥合全球差距的一个有希望的战略;解决疫苗犹豫问题可能会增加疫苗接种覆盖率;减毒活疫苗、鼻内给药和通用疫苗是未来的发展方向。这些见解突出了改善流感疫苗覆盖率的潜在途径,并为减轻疫苗犹豫的战略提供信息,这对保护儿童和加强公共卫生至关重要。
期刊介绍:
(formerly Human Vaccines; issn 1554-8619)
Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics.
Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.