Complications of total ankle arthroplasty versus ankle arthrodesis: A systematic review and meta-analysis with trial sequential analysis.

IF 1.9 3区 医学 Q2 ORTHOPEDICS Foot and Ankle Surgery Pub Date : 2024-12-16 DOI:10.1016/j.fas.2024.11.008
Jonathan Jia En Boey, Rui Xiang Toh, Yao Chen Loh, Chen Zhang, Ryan Ruiyang Ling, Zong Xian Li, Kizher Shajahan Mohamed Buhary, Kae Sian Tay
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Abstract

Background: Ankle osteoarthritis affects 1-3 % of all adults. Contemporary evidence is equivocal when comparing the outcomes and complications of TAA and AA. This review aims to compare the complications between TAA and AA to provide surgeons with an additional perspective when managing ESAO.

Methods: We conducted a systematic review and meta-analysis, searching four international databases from inception until 21 Jan 2024 for RCTs and score-matched studies reporting on TAA or AA for ESAO. Score-matched studies were included if matching accounted for four or more covariates related to patient demographics and comorbidities. Random-effects (DerSimonian and Laird) meta-analyses were conducted. The primary outcome was complications stratified into total, major, and minor as guided by previous studies. We rated intra-study risk of bias using the Cochrane Risk of Bias 2 tool and the Newcastle-Ottawa Scale. We assessed the certainty of evidence using the GRADE approach.

Results: 5 studies (2 RCTs and 3 score-matched studies) totalling 13,957 patients (6975 TAA, 6982 AA) were included in the meta-analysis. The pooled RR for total complications was 0.95 (95 %-CI: 0.85 to 1.08, p = 0.45, moderate certainty, favourable towards AA). The pooled RR for major complications was 1.18 (95 %-CI: 0.70 to 1.98; p = 0.54, low certainty, favouring TAA) and for minor complications was 0.96 (95 %-CI: 0.75 to 1.22; p = 0.73, moderate certainty, favouring AA).

Conclusion: Previous reviews have recognised TAA and AA as equivocally effective surgical options for patients with ESAO. Our review may suggest that TAA and AA have similar rates of major and minor complications. Surgeons should consider the specific complications for TAA and AA despite the similar rates of complications when counselling patients.

Protocol registration: CRD42023389626.

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全踝关节置换术与踝关节融合术的并发症:系统回顾和荟萃分析与试验序列分析。
背景:踝关节骨关节炎影响所有成年人的1- 3%。在比较TAA和AA的结果和并发症时,当代证据是模棱两可的。本综述旨在比较TAA和AA之间的并发症,为外科医生治疗ESAO提供额外的视角。方法:我们进行了系统回顾和荟萃分析,检索了四个国际数据库,从建立到2024年1月21日,检索了报告TAA或AA治疗ESAO的随机对照试验和评分匹配研究。如果匹配包含4个或更多与患者人口统计学和合并症相关的协变量,则纳入评分匹配的研究。随机效应(DerSimonian和Laird)荟萃分析。根据以往的研究,主要结局是并发症分为总、主要和次要。我们使用Cochrane risk of bias 2工具和Newcastle-Ottawa量表评定研究内偏倚风险。我们使用GRADE方法评估证据的确定性。结果:meta分析纳入5项研究(2项rct和3项评分匹配研究),共13957例患者(6975例TAA, 6982例AA)。总并发症的合并RR为0.95 (95% -CI: 0.85 ~ 1.08, p = 0.45,中度确定性,有利于AA)。主要并发症的合并RR为1.18 (95% -CI: 0.70 ~ 1.98;p = 0.54,低确定性,支持TAA),轻微并发症为0.96 (95% -CI: 0.75至1.22;p = 0.73,中等确定性,支持AA)。结论:以前的综述已经认识到TAA和AA是ESAO患者的模棱两可的有效手术选择。我们的回顾可能表明TAA和AA有相似的主要和次要并发症发生率。外科医生在咨询患者时应考虑TAA和AA的具体并发症,尽管并发症发生率相似。协议注册:CRD42023389626。
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来源期刊
Foot and Ankle Surgery
Foot and Ankle Surgery ORTHOPEDICS-
CiteScore
4.60
自引率
16.00%
发文量
202
期刊介绍: Foot and Ankle Surgery is essential reading for everyone interested in the foot and ankle and its disorders. The approach is broad and includes all aspects of the subject from basic science to clinical management. Problems of both children and adults are included, as is trauma and chronic disease. Foot and Ankle Surgery is the official journal of European Foot and Ankle Society. The aims of this journal are to promote the art and science of ankle and foot surgery, to publish peer-reviewed research articles, to provide regular reviews by acknowledged experts on common problems, and to provide a forum for discussion with letters to the Editors. Reviews of books are also published. Papers are invited for possible publication in Foot and Ankle Surgery on the understanding that the material has not been published elsewhere or accepted for publication in another journal and does not infringe prior copyright.
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