Comparative Retrospective Study of PLLA and PLLA/HA Pins for Osteochondral Fragment Fixation in Osteochondral Lesion of the Talus.

Foot & ankle international Pub Date : 2025-02-01 Epub Date: 2024-12-20 DOI:10.1177/10711007241303757
Dan Moriwaki, Tomoyuki Nakasa, Yasunari Ikuta, Shingo Kawabata, Saori Ishibashi, Satoru Sakurai, Nobuo Adachi
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Abstract

Background: Postoperative osteolysis may be observed around poly-l-lactic acid (PLLA) pins in osteochondral fragments fixation for an osteochondral lesion of the talus (OLT). Hydroxyapatite (HA) improves biocompatibility, osteoconductivity, and mechanical strength when added to PLLA. This study aimed to compare the characteristics of osteolysis and clinical outcomes of fixation for OLT with PLLA pins vs PLLA/HA pins.

Methods: Thirty-one ankles undergoing fixation with bioabsorbable pins for OLT were included. Fourteen ankles were fixed with PLLA/HA pins and 17 ankles with PLLA pins. Magnetic resonance imaging (MRI) was taken pre- and postoperatively at 1 year. Osteolysis around pins, bone marrow edema (BME) in the talus, and pin insertion angle on MRI, the American Orthopaedic Foot & Ankle Society (AOFAS) score, and the visual analog scale (VAS) pain score were compared between the 2 groups pre- and postoperatively at 1 year. AOFAS score at the final follow-up was also compared between the 2 groups.

Results: The osteolysis area was significantly smaller in the PLLA/HA group in both coronal and sagittal planes on MRIs obtained 1 year postoperatively. There were no significant differences in osteolysis frequency, BME area, AOFAS score, and VAS pain score. Lower pin insertion angles measured on either sagittal or coronal planes were generally associated with greater amounts of osteolysis.

Conclusion: We did not find superiority using PLLA/HA pins compared with PLLA pins to fixate talar osteochondral fragments. However, PLLA/HA pin use was associated with less osteolysis around pins compared with PLLA pins.

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PLLA与PLLA/HA钉固定距骨软骨损伤骨软骨碎片的回顾性比较研究。
背景:在距骨软骨病变(OLT)的骨软骨碎片固定中,术后聚l-乳酸(PLLA)钉周围可能观察到骨溶解。羟基磷灰石(HA)添加到pla中可改善生物相容性、骨导电性和机械强度。本研究旨在比较PLLA针与PLLA/HA针固定OLT的骨溶解特点和临床结果。方法:采用生物吸收针固定踝关节进行OLT。14个踝关节用PLLA/HA针固定,17个踝关节用PLLA针固定。术前、术后1年分别行磁共振成像(MRI)检查。比较两组患者术后1年的针周围骨溶解、距骨骨髓水肿(BME)、针植入角度、美国骨科足踝学会(AOFAS)评分、视觉模拟评分(VAS)疼痛评分。比较两组患者最终随访时的AOFAS评分。结果:术后1年的mri显示,PLLA/HA组冠状面和矢状面骨溶解面积均明显缩小。两组在骨溶解频率、BME面积、AOFAS评分、VAS疼痛评分方面无显著差异。在矢状面或冠状面测量较低的针插入角度通常与较大程度的骨溶解有关。结论:应用PLLA/HA针固定距骨软骨碎片与应用PLLA针固定距骨软骨碎片并无明显优势。然而,与PLLA针相比,使用PLLA/HA针与较少的针周围骨溶解相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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