Infected Primary Bone Mantle Cell Lymphoma with Multiple Vertebral Involvement.

Rebeh Bougossa, Fatma Larbi, Asma Ben Mabrouk, Olfa Jomaa, Jihene Chelli
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Abstract

Primary vertebral lymphoma is an exceedingly rare entity. We hereby report a case of a 67-year-old male who presented to our department with fever, weight loss, and progressively worsening lower back pain radiating to the right hip. Physical examination showed pain on percussion of the dorsal and lumbar spine and tenderness on palpation of the right upper thigh area. The radiographic findings revealed numerous vertebral lesions with a right psoas abscess extending to the right upper thigh. Intravenous antibiotic therapy was initiated and the patient underwent an incision and drainage of the psoas abscess with a favourable outcome. However, given the suspicious imaging findings of the osseous lesions suggestive of malignancy, a vertebral biopsy was performed and yielded histo-pathological findings consistent with bone mantle cell lymphoma. To the best of our knowledge, this is the first case of an infected primary bone mantle cell lymphoma with multiple vertebral involvement. The diagnosis is challenging and can be confused with other diseases.

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累及多个椎体的感染原发性骨套细胞淋巴瘤。
原发性椎体淋巴瘤是一种极为罕见的疾病。我们在此报告一例67岁男性患者,他以发热、体重减轻和逐渐恶化的腰痛向右髋部放射就诊。体格检查显示脊背和腰椎触痛,右大腿上部触痛。x线表现显示许多椎体病变,右腰肌脓肿延伸至右大腿上部。开始静脉注射抗生素治疗,患者接受腰肌脓肿切开引流,结果良好。然而,考虑到可疑的骨病变影像学结果提示恶性肿瘤,我们进行了椎体活检,结果显示组织病理结果与骨套细胞淋巴瘤一致。据我们所知,这是第一例感染原发性骨套细胞淋巴瘤累及多椎体的病例。诊断具有挑战性,并可能与其他疾病混淆。
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