Cellular Schwannoma of the Palate Simulating as Malignant Peripheral Nerve Sheath Tumor: A Diagnostic Marathon.

Manas Bajpai, Amit Mani, Saurabh L Sabnis, Vatchala Rani Rm
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Abstract

Schwannomas are considered benign soft tissue tumors that originate from Schwann cells. Oral Schwannomas are rare and account for only 1% of all Schwannomas. Cellularschwannoma (CS) is a rare histological variant of schwannoma, characterized by high cellularity and cellular atypia. We present a case of localized growth of palatal mucosa that imitated the features of malignant peripheral nerve sheath tumor (MPNST) on histopathological examination; it was differentiated from MPNST by the correlation of clinical, histopathological, and immunohistochemical features.

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模拟恶性周围神经鞘肿瘤的上颚细胞神经鞘瘤:一场诊断马拉松。
神经鞘瘤被认为是起源于雪旺细胞的良性软组织肿瘤。口腔神经鞘瘤很少见,仅占所有神经鞘瘤的1%。细胞性神经鞘瘤(CS)是一种罕见的神经鞘瘤的组织学变异,其特点是高细胞性和细胞异型性。我们报告一例腭黏膜局部生长的病例,在组织病理学检查上模仿恶性周围神经鞘瘤(MPNST)的特征;通过临床、组织病理学和免疫组织化学特征的相关性,将其与MPNST区分开来。
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