Louise Bering, Line Dam Heftdal, Safura-Luise Heidari, Sebastian Rask Hamm, Cecillie Bo Hansen, Dina Leth Møller, Mia Pries-Heje, Kamille Fogh, Rasmus Bo Hasselbalch, Laura Pérez-Alós, Jan Gerstoft, Thomas Benfield, Selina Kikkenborg Berg, Anne Vinggaard Christensen, Nina Marie Birk, Linda Maria Hilsted, Sisse Rye Ostrowski, Ruth Frikke-Schmidt, Erik Sørensen, Kirsten Grønbæk, Henning Bundgaard, Kasper Iversen, Peter Garred, Susanne Dam Nielsen
{"title":"Humoral response 24 months after the first COVID-19 vaccination in people with HIV with and without diabetes.","authors":"Louise Bering, Line Dam Heftdal, Safura-Luise Heidari, Sebastian Rask Hamm, Cecillie Bo Hansen, Dina Leth Møller, Mia Pries-Heje, Kamille Fogh, Rasmus Bo Hasselbalch, Laura Pérez-Alós, Jan Gerstoft, Thomas Benfield, Selina Kikkenborg Berg, Anne Vinggaard Christensen, Nina Marie Birk, Linda Maria Hilsted, Sisse Rye Ostrowski, Ruth Frikke-Schmidt, Erik Sørensen, Kirsten Grønbæk, Henning Bundgaard, Kasper Iversen, Peter Garred, Susanne Dam Nielsen","doi":"10.1097/QAD.0000000000004026","DOIUrl":null,"url":null,"abstract":"<p><p>People with HIV (PWH) and people with diabetes mellitus have increased risk of severe COVID-19, but little is known about humoral response to COVID-19 vaccines in PWH with DM. We investigated SARS-CoV-2 antireceptor-binding domain (anti-RBD) immunoglobulin G (IgG) geometrical concentrations and neutralizing antibody capacity (nAB) in PWH with and without diabetes mellitus. Anti-RBD IgG and nAB in COVID-19-vaccinated PWH were not associated with diabetes mellitus-status or HbA1c 24 months after the initial COVID-19 vaccination.</p>","PeriodicalId":7502,"journal":{"name":"AIDS","volume":"38 15","pages":"2100-2103"},"PeriodicalIF":3.4000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"AIDS","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/QAD.0000000000004026","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/14 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
People with HIV (PWH) and people with diabetes mellitus have increased risk of severe COVID-19, but little is known about humoral response to COVID-19 vaccines in PWH with DM. We investigated SARS-CoV-2 antireceptor-binding domain (anti-RBD) immunoglobulin G (IgG) geometrical concentrations and neutralizing antibody capacity (nAB) in PWH with and without diabetes mellitus. Anti-RBD IgG and nAB in COVID-19-vaccinated PWH were not associated with diabetes mellitus-status or HbA1c 24 months after the initial COVID-19 vaccination.
期刊介绍：
Publishing the very latest ground breaking research on HIV and AIDS. Read by all the top clinicians and researchers, AIDS has the highest impact of all AIDS-related journals. With 18 issues per year, AIDS guarantees the authoritative presentation of significant advances. The Editors, themselves noted international experts who know the demands of your work, are committed to making AIDS the most distinguished and innovative journal in the field. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.
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