Design, synthesis, and characterization of an Ag–Bi–S-based multifunctional nanotheranostic platform†

IF 6.1 3区 医学 Q1 MATERIALS SCIENCE, BIOMATERIALS Journal of Materials Chemistry B Pub Date : 2024-12-18 DOI:10.1039/D4TB02502D
Yuan-Yi Tan, Xin Chen, Dong-Yun Zheng, Chao Liu, Xiao-Jun Liu, Xian-Guang Lin and Chun-Nan Zhu
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Abstract

This paper reports an Ag–Bi–S-based nanotheranostic platform with an ingeniously designed heterostructure, an appropriate size, and good imaging and therapy performances. By comparing the fluorescence property and Bi element content, the optimal heterostructure was demonstrated to be Ag2S/Bi2S3 core/shell. The hydrophilic Ag2S/Bi2S3-PEG nanocrystals with hydrodynamic diameter of 37.56 nm exhibited near-infrared-II fluorescence, good CT imaging contrast, and a high photothermal conversion efficiency (38.4%), and have shown significant potential in the precision diagnosis and treatment of tumors.

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基于银铋的多功能纳米治疗平台的设计、合成和表征。
本文报道了一种异质结构设计巧妙、尺寸合适、具有良好成像和治疗性能的银铋基纳米治疗平台。通过比较其荧光性质和Bi元素含量,确定了最佳异质结构为Ag2S/Bi2S3核/壳。水动力直径为37.56 nm的亲水性Ag2S/Bi2S3-PEG纳米晶体具有近红外荧光、良好的CT成像对比度和较高的光热转换效率(38.4%),在肿瘤的精确诊断和治疗中具有重要的潜力。
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来源期刊
Journal of Materials Chemistry B
Journal of Materials Chemistry B MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
11.50
自引率
4.30%
发文量
866
期刊介绍: Journal of Materials Chemistry A, B & C cover high quality studies across all fields of materials chemistry. The journals focus on those theoretical or experimental studies that report new understanding, applications, properties and synthesis of materials. Journal of Materials Chemistry A, B & C are separated by the intended application of the material studied. Broadly, applications in energy and sustainability are of interest to Journal of Materials Chemistry A, applications in biology and medicine are of interest to Journal of Materials Chemistry B, and applications in optical, magnetic and electronic devices are of interest to Journal of Materials Chemistry C.Journal of Materials Chemistry B is a Transformative Journal and Plan S compliant. Example topic areas within the scope of Journal of Materials Chemistry B are listed below. This list is neither exhaustive nor exclusive: Antifouling coatings Biocompatible materials Bioelectronics Bioimaging Biomimetics Biomineralisation Bionics Biosensors Diagnostics Drug delivery Gene delivery Immunobiology Nanomedicine Regenerative medicine & Tissue engineering Scaffolds Soft robotics Stem cells Therapeutic devices
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Back cover Back cover Correction: In vivo transplantation of intrahepatic cholangiocyte organoids with decellularized liver-derived hydrogels supports hepatic cellular proliferation and differentiation in chronic liver injury Back cover Correction: Preventing biofilm formation and eradicating pathogenic bacteria by Zn doped histidine derived carbon quantum dots
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