Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxy-PEP-Eligible Population

Rachel Mittelstaedt, Sanjat Kanjilal, David Helekal, Gregory K Robbins, Yonatan H Grad
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Abstract

Among doxycycline post-exposure prophylaxis (doxy-PEP) eligible men, Staphylococcus aureus tetracycline non-susceptibility is more prevalent than in the overall population and is associated with resistance to trimethoprim-sulfamethoxazole and clindamycin. Doxy-PEP may select for multi-drug-resistant S. aureus, underscoring the importance of surveillance.
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在符合doxy - pep条件的人群中,金黄色葡萄球菌对四环素的耐药性和共耐药性
在多西环素暴露后预防(doxy-PEP)符合条件的男性中,金黄色葡萄球菌四环素不敏感性比总体人群更为普遍,并与对甲氧苄氨嘧啶-磺胺甲恶唑和克林霉素的耐药有关。Doxy-PEP可能选择耐多药金黄色葡萄球菌,强调监测的重要性。
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